Literature DB >> 10885020

[Pharmacological reminder of the emotional condition facilitates the amnestic memory trace retrieval].

A S Bazian1, V M Getsova, N V Orlova.   

Abstract

Passive avoidance reflex was shown to be differently reproduced in rats. The reproduction was more stable in rats with a higher level of learning. Amnestic effects induced seizures were shown to depend on relationships between the intensity of learning and the intensity of seizures. Unconditioned stimuli acting as a reminder decreased the amnestic effects of seizures. Learning process significantly reduced the seizure severity. A dissociated convulsive state was reproduced with the aid of a pharmacological reminder of anxiety formed in the course of learning. Haloperidol produced anxiety and suppressed amnestic effects of seizures, facilitated conditioning in rats with a low level of learning.

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Year:  2000        PMID: 10885020

Source DB:  PubMed          Journal:  Ross Fiziol Zh Im I M Sechenova        ISSN: 0869-8139


  1 in total

1.  The pentylenetetrazole allosteric component of the GABAA receptor plasticity.

Authors:  A S Bazyan; V I Mel'nik; L S Bikbulatova; M N Karpova
Journal:  Dokl Biol Sci       Date:  2002 Sep-Oct
  1 in total

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