Literature DB >> 10881768

Drug-facilitated sexual assault ('date rape').

R H Schwartz1, R Milteer, M A LeBeau.   

Abstract

In the past few years, drug-facilitated sexual assaults have received widespread media coverage. In addition to alcohol, the most frequently used date-rape drug, flunitrazepam (Rohypnol), a fast-acting benzodiazepine, and gamma-hydroxybutyrate (GHB) and its congeners are among the most popular drugs used for this purpose. The latter drug is easily procured at some gymnasiums, popular bars, discos, and rave clubs, as well as over the Internet. Perpetrators choose these drugs because they act rapidly, produce disinhibition and relaxation of voluntary muscles, and cause the victim to have lasting anterograde amnesia for events that occur under the influence of the drug. Alcoholic beverages potentiate the drug effects. We review several date-rape drugs, provide information on laboratory testing for them, and offer guidelines for preventing drug-facilitated sexual assault.

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Year:  2000        PMID: 10881768

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  22 in total

1.  Drug-facilitated date rape.

Authors:  E Weir
Journal:  CMAJ       Date:  2001-07-10       Impact factor: 8.262

2.  Traumatic brain injury after a motor vehicle accident: fact or "fantasy"?

Authors:  D G Caldicott; N Edwards
Journal:  Emerg Med J       Date:  2001-11       Impact factor: 2.740

3.  GHB-Induced Cognitive Deficits During Adolescence and the Role of NMDA Receptor.

Authors:  R Sircar; L-C Wu; K Reddy; D Sircar; A K Basak
Journal:  Curr Neuropharmacol       Date:  2011-03       Impact factor: 7.363

4.  Behavioral effects of gamma-hydroxybutyrate in humans.

Authors:  Alison Oliveto; William Brooks Gentry; Rhonda Pruzinsky; Kishorchandra Gonsai; Thomas R Kosten; Bridget Martell; James Poling
Journal:  Behav Pharmacol       Date:  2010-07       Impact factor: 2.293

5.  Involvement of gamma-hydroxybutyrate (GHB) and GABA-B receptors in the acute behavioral effects of GHB in baboons.

Authors:  Amy K Goodwin; Wolfgang Froestl; Elise M Weerts
Journal:  Psychopharmacology (Berl)       Date:  2005-03-01       Impact factor: 4.530

6.  γ-Hydroxybutyric Acid (GHB) Pharmacokinetics and Pharmacodynamics: Semi-Mechanistic and Physiologically Relevant PK/PD Model.

Authors:  Rutwij A Dave; Kristin E Follman; Marilyn E Morris
Journal:  AAPS J       Date:  2017-06-26       Impact factor: 4.009

7.  Effects of gamma-hydroxybutyric acid on spatial learning and memory in adolescent and adult female rats.

Authors:  Ratna Sircar; Ashim Basak; Debashish Sircar; Li-Cheng Wu
Journal:  Pharmacol Biochem Behav       Date:  2010-05-09       Impact factor: 3.533

8.  Mechanistic toxicokinetic model for gamma-hydroxybutyric acid: inhibition of active renal reabsorption as a potential therapeutic strategy.

Authors:  Melanie A Felmlee; Qi Wang; Dapeng Cui; Samuel A Roiko; Marilyn E Morris
Journal:  AAPS J       Date:  2010-05-12       Impact factor: 4.009

9.  Comparative abuse liability of GHB and ethanol in humans.

Authors:  Matthew W Johnson; Roland R Griffiths
Journal:  Exp Clin Psychopharmacol       Date:  2013-02-18       Impact factor: 3.157

Review 10.  Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid.

Authors:  Marilyn E Morris; Melanie A Felmlee
Journal:  AAPS J       Date:  2008-06-04       Impact factor: 4.009

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