| Literature DB >> 10880887 |
C S McLachlan1, J L Yin, C Driussi, P R Jusuf, B Hambly, M A McGuire.
Abstract
Cells that are apoptotic and comprise less than 2% of the total cellular population are difficult to detect by conventional methods (i.e., DNA ladder). We discuss a new methodological technique, PCR-amplified DNA ladder, to detect very low levels of DNA fragmentation (indicative of apoptosis) in a myocardial infarct heart failure model. Results and methodology are contrasted with the traditional DNA ladder technique.Entities:
Mesh：
Year: 2000 PMID： 10880887 DOI： 10.2170/jjphysiol.50.281
Source DB: PubMed Journal: Jpn J Physiol ISSN： 0021-521X