| Literature DB >> 10880769 |
R A Kroes1, A Jastrow, M G McLone, H Yamamoto, P Colley, D S Kersey, V W Yong, E Mkrdichian, L Cerullo, J Leestma, J R Moskal.
Abstract
A two-step strategy was developed consisting of differential display reverse transcriptase polymerase chain reaction (DDRT-PCR) with cultured normal human fetal astrocytes and U-373MG glioma cells followed by reverse Northern analysis of normal brain and primary tumor tissues. hu-dek, alpha-NAC, ribosomal proteins L7a and L35a, and five novel genes were identified. Since none of these genes has been previously shown to be associated with malignant brain tumor formation, this approach may be useful to identify novel targets for the diagnosis and treatment of brain tumors.Entities:
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Year: 2000 PMID： 10880769 DOI： 10.1016/s0304-3835(00)00462-6
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679