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95 in total

Review 1. Recent advances: Psychiatry.

Authors: D Lyons; D M McLoughlin
Journal: BMJ Date: 2001-11-24

Review 2. Protein aggregates and dementia: is there a common toxicity?

Authors: S Lovestone; D M McLoughlin
Journal: J Neurol Neurosurg Psychiatry Date: 2002-02 Impact factor: 10.154

3. Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.

Authors: William P Esler; W Taylor Kimberly; Beth L Ostaszewski; Wenjuan Ye; Thekla S Diehl; Dennis J Selkoe; Michael S Wolfe
Journal: Proc Natl Acad Sci U S A Date: 2002-02-26 Impact factor: 11.205

4. Notch receptor cleavage depends on but is not directly executed by presenilins.

Authors: Yoshihito Taniguchi; Helena Karlström; Johan Lundkvist; Tomohiko Mizutani; Akira Otaka; Monica Vestling; Alan Bernstein; Dorit Donoviel; Urban Lendahl; Tasuku Honjo
Journal: Proc Natl Acad Sci U S A Date: 2002-03-12 Impact factor: 11.205

5. The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.

Authors: Roberta Roncarati; Nenad Sestan; Meir H Scheinfeld; Bridget E Berechid; Peter A Lopez; Olimpia Meucci; Jane C McGlade; Pasko Rakic; Luciano D'Adamio
Journal: Proc Natl Acad Sci U S A Date: 2002-05-14 Impact factor: 11.205

10. Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production.

Authors: Kei Suga; Takami Tomiyama; Hiroshi Mori; Kimio Akagawa
Journal: Biochem J Date: 2004-08-01 Impact factor: 3.857

Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1.

Review 1. Recent advances: Psychiatry.

Review 2. Protein aggregates and dementia: is there a common toxicity?

3. Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.

4. Notch receptor cleavage depends on but is not directly executed by presenilins.

5. The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.

6. Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation.

7. Traumatic Brain Injury Alters the Metabolism and Facilitates Alzheimer's Disease in a Murine Model.

8. The presenilins turned inside out: implications for their structures and functions.

9. A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish.

10. Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production.