Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors.

× No keyword cloud information.

52 in total

1. A novel phenylpyridazinone, T-3999, reduces the progression of autoimmune myocarditis to dilated cardiomyopathy.

Authors: Fadia Ali Kamal; Kenichi Watanabe; Meilei Ma; Yuichi Abe; Reyad Elbarbary; Makoto Kodama; Yoshifusa Aizawa
Journal: Heart Vessels Date: 2010-10-05 Impact factor: 2.037

Review 2. Modulation of T cell immune functions by the prostaglandin E(2) - cAMP pathway in chronic inflammatory states.

Authors: Kristoffer Watten Brudvik; Kjetil Taskén
Journal: Br J Pharmacol Date: 2012-05 Impact factor: 8.739

Review 3. Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.

Authors: Adam Lerner; Paul M Epstein
Journal: Biochem J Date: 2006-01-01 Impact factor: 3.857

4. The PDE4 inhibitor rolipram prevents NF-kappaB binding activity and proinflammatory cytokine release in human chorionic cells.

Authors: Roxane Hervé; Thomas Schmitz; Danièle Evain-Brion; Dominique Cabrol; Marie-Josèphe Leroy; Céline Méhats
Journal: J Immunol Date: 2008-08-01 Impact factor: 5.422

Review 5. Chronic obstructive pulmonary disease * 12: New treatments for COPD.

Authors: P J Barnes
Journal: Thorax Date: 2003-09 Impact factor: 9.139

6. Assessing protein-ligand binding modes with computational tools: the case of PDE4B.

Authors: Gülşah Çifci; Viktorya Aviyente; E Demet Akten; Gerald Monard
Journal: J Comput Aided Mol Des Date: 2017-05-22 Impact factor: 3.686

Review 7. Congenital nephrogenic diabetes insipidus: the current state of affairs.

Authors: Daniel Wesche; Peter M T Deen; Nine V A M Knoers
Journal: Pediatr Nephrol Date: 2012-03-17 Impact factor: 3.714

8. Ferulic acid prevents LPS-induced up-regulation of PDE4B and stimulates the cAMP/CREB signaling pathway in PC12 cells.

Authors: Hao Huang; Qian Hong; Hong-Ling Tan; Cheng-Rong Xiao; Yue Gao
Journal: Acta Pharmacol Sin Date: 2016-09-26 Impact factor: 6.150

9. Pharmacophore modeling, 3D-QSAR, and docking study of pyrozolo[1,5-a]pyridine/4,4-dimethylpyrazolone analogues as PDE4 selective inhibitors.

Authors: Naga Srinivas Tripuraneni; Mohammed Afzal Azam
Journal: J Mol Model Date: 2015-10-26 Impact factor: 1.810

10. Enantiomer discrimination illustrated by the high resolution crystal structures of type 4 phosphodiesterase.

Authors: Qing Huai; Yingjie Sun; Huanchen Wang; Dwight Macdonald; Renée Aspiotis; Howard Robinson; Zheng Huang; Hengming Ke
Journal: J Med Chem Date: 2006-03-23 Impact factor: 7.446