Literature DB >> 10878198

Aortic aneurysm and dissection are not associated with an increased risk for giant cell arteritis/ polymyalgia rheumatica.

M Ehrenfeld1, R Bitzur, J Schneiderman, A Smolinsky, Y Sidi, H Gur.   

Abstract

It has recently been claimed that giant cell arteritis (GCA) is associated with a markedly increased risk of aortic aneurysm formation or rupture. In the present study, the opposite approach was taken, by looking for the incidence of GCA and polymyalgia rheumatica (PMR) in patients with aortic aneurysm, aortic dissection, or both (AA/D). The records of 315 consecutive patients admitted with the diagnosis of AA/D were reviewed. In addition, follow up information was obtained in 82 patients by examination in the outpatient clinic. After careful examination and assessment of clinical and laboratory data, it was found that none of the 82 patients who survived hospitalisation and were available for examination had GCA or PMR. Moreover, review of the retrospective data available from hospital records of the total consecutive 315 patients with AA/D failed to find any patient with a diagnosis of GCA/PMR. In conclusion, the present study did not find an increased prevalence of GCA/PMR among a cohort of Israeli patients with AA/D. Therefore, it is suggested that a thorough investigation aiming to diagnose GCA/PMR is not cost effective in most of the elderly patients presenting with AA/D.

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Year:  2000        PMID: 10878198      PMCID: PMC1741660          DOI: 10.1136/pmj.76.897.409

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  18 in total

1.  Long-term follow-up of polymyalgia rheumatica: evidence for synovitis.

Authors:  L A Healey
Journal:  Semin Arthritis Rheum       Date:  1984-05       Impact factor: 5.532

2.  Epidemiology of temporal arteritis in Israel.

Authors:  G Friedman; B Friedman; J Benbassat
Journal:  Isr J Med Sci       Date:  1982-02

3.  Increased incidence of aortic aneurysm and dissection in giant cell (temporal) arteritis. A population-based study.

Authors:  J M Evans; W M O'Fallon; G G Hunder
Journal:  Ann Intern Med       Date:  1995-04-01       Impact factor: 25.391

4.  Giant cell arteritis in Jerusalem: a 12-year epidemiological study.

Authors:  M Sonnenblick; G Nesher; Y Friedlander; A Rubinow
Journal:  Br J Rheumatol       Date:  1994-10

5.  The HLA-DRB1 locus as a genetic component in giant cell arteritis. Mapping of a disease-linked sequence motif to the antigen binding site of the HLA-DR molecule.

Authors:  C M Weyand; K C Hicok; G G Hunder; J J Goronzy
Journal:  J Clin Invest       Date:  1992-12       Impact factor: 14.808

6.  HLA-DRB1 alleles in polymyalgia rheumatica, giant cell arteritis, and rheumatoid arthritis.

Authors:  C M Weyand; N N Hunder; K C Hicok; G G Hunder; J J Goronzy
Journal:  Arthritis Rheum       Date:  1994-04

7.  Aortic and extracranial large vessel giant cell arteritis: a review of 72 cases with histopathologic documentation.

Authors:  J T Lie
Journal:  Semin Arthritis Rheum       Date:  1995-06       Impact factor: 5.532

8.  Illustrated histopathologic classification criteria for selected vasculitis syndromes. American College of Rheumatology Subcommittee on Classification of Vasculitis.

Authors:  J T Lie
Journal:  Arthritis Rheum       Date:  1990-08

9.  Trends in incidence and clinical presentation of temporal arteritis in Olmsted County, Minnesota, 1950-1985.

Authors:  E B Machado; C J Michet; D J Ballard; G G Hunder; C M Beard; C P Chu; W M O'Fallon
Journal:  Arthritis Rheum       Date:  1988-06

10.  Thoracic aortic aneurysm and rupture in giant cell arteritis. A descriptive study of 41 cases.

Authors:  J M Evans; C A Bowles; J Bjornsson; C J Mullany; G G Hunder
Journal:  Arthritis Rheum       Date:  1994-10
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