Literature DB >> 10876992

Population data on 6 short tandem repeat loci in a sample of Caucasian-Mestizos from Colombia.

J J Yunis1, O García, I Uriarte, E J Yunis.   

Abstract

Blood samples from 409-452 unrelated Colombian Caucasian-Mestizo individuals were amplified and typed for six short tandem repeat (STR) markers (HUMF13A01, HUMFES/FPS, HUMVWA, HUMCSF1PO, HUMTPOX, HUMTH01). The allele frequencies, genotype frequencies, heterozygosity, mean paternity exclusion chance, polymorphism information content, discrimination power, assumption of independence within and between loci and Hardy Weinberg equilibrium were determined. The results demonstrate that all markers conform to Hardy-Weinberg equilibrium expectations. In addition, the results demonstrate the assumption of independence within and between the loci analysed. The mean exclusion chance (MEC) was 0.9851 for all six STR loci analysed and the discrimination power (DP) was 0.9999973. Therefore, this Colombian population database can be used in identity testing to estimate the frequency of a multiple PCR-based locus DNA profile in forensic cases as well as in paternity testing.

Mesh:

Year:  2000        PMID: 10876992     DOI: 10.1007/s004140050293

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  3 in total

1.  Association study of polymorphisms in LRP1, tau and 5-HTT genes and Alzheimer's disease in a sample of Colombian patients.

Authors:  D A Forero; G Arboleda; J J Yunis; R Pardo; H Arboleda
Journal:  J Neural Transm (Vienna)       Date:  2005-12-14       Impact factor: 3.575

2.  Mitochondrial DNA (mtDNA) haplogroups in 1526 unrelated individuals from 11 Departments of Colombia.

Authors:  Juan J Yunis; Emilio J Yunis
Journal:  Genet Mol Biol       Date:  2013-08-30       Impact factor: 1.771

3.  IL18 Gene Variants Influence the Susceptibility to Chagas Disease.

Authors:  Daniel A Leon Rodriguez; F David Carmona; Luis Eduardo Echeverría; Clara Isabel González; Javier Martin
Journal:  PLoS Negl Trop Dis       Date:  2016-03-30
  3 in total

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