| Literature DB >> 10876850 |
L I Pavlova1, M A Gorbunov, M S Vorob'eva, A S Karavanov, V P Grachev, I P Ladyshenskaia, M N Rasshchepkina, L N Mel'nikova, T M Lebedeva, N A Mel'nikov, A G Gusmanova, M Iu Deviatkov, E V Rozanova, M A Mukachev.
Abstract
The word deals with the results obtained in the study of the reactogenicity and immunological activity of concentrated and inactivated tissue-culture tick-borne encephalitis vaccine, manufactured by the Chumakov Institute of Poliomyelitis and Viral Encephalitides, in the immunization of children and adolescents. The vaccine proved to be moderately reactogenic and exhibited pronounced immunological activity. In 91.5% of the immunized children the fourfold increase of the antibody level was observed. On the basis of the data obtained in this study the tick-borne encephalitis vaccine was recommended for use in medical practice for the prophylaxis of tick-borne encephalitis among children and adolescents.Entities:
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Year: 1999 PMID： 10876850
Source DB: PubMed Journal: Zh Mikrobiol Epidemiol Immunobiol ISSN： 0372-9311