Literature DB >> 10875924

A subset of viral transcripts packaged within human cytomegalovirus particles.

W A Bresnahan1, T Shenk.   

Abstract

A human cytomegalovirus gene array was used to identify a previously unidentified class of viral transcripts. These transcripts, termed virion RNAs, were packaged within infectious virions and were delivered to the host cell on infection. This mechanism of herpesvirus gene expression allows for viral genes to be expressed within an infected cell immediately after virus entry and in the absence of transcription from the viral genome.

Entities:  

Mesh:

Substances:

Year:  2000        PMID: 10875924     DOI: 10.1126/science.288.5475.2373

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  83 in total

1.  UL82 virion protein activates expression of immediate early viral genes in human cytomegalovirus-infected cells.

Authors:  W A Bresnahan; T E Shenk
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

2.  Experimental preemptive immunotherapy of murine cytomegalovirus disease with CD8 T-cell lines specific for ppM83 and pM84, the two homologs of human cytomegalovirus tegument protein ppUL83 (pp65).

Authors:  R Holtappels; J Podlech; N K Grzimek; D Thomas; M F Pahl-Seibert; M J Reddehase
Journal:  J Virol       Date:  2001-07       Impact factor: 5.103

3.  Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene.

Authors:  Dong Yu; Gregory A Smith; Lynn W Enquist; Thomas Shenk
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

4.  Identification of human herpesvirus 6 latency-associated transcripts.

Authors:  Kazuhiro Kondo; Kazuya Shimada; Junji Sashihara; Keiko Tanaka-Taya; Koichi Yamanishi
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

5.  RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions.

Authors:  M T Sciortino; M Suzuki; B Taddeo; B Roizman
Journal:  J Virol       Date:  2001-09       Impact factor: 5.103

6.  Functional map of human cytomegalovirus AD169 defined by global mutational analysis.

Authors:  Dong Yu; Maria C Silva; Thomas Shenk
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-30       Impact factor: 11.205

7.  Might a vanguard of mRNAs prepare cells for the arrival of herpes simplex virus?

Authors:  Thomas Shenk
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-25       Impact factor: 11.205

8.  SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replication.

Authors:  Michael Nevels; Wolfram Brune; Thomas Shenk
Journal:  J Virol       Date:  2004-07       Impact factor: 5.103

9.  Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication.

Authors:  Hiroki Isomura; Tatsuya Tsurumi; Mark F Stinski
Journal:  J Virol       Date:  2004-12       Impact factor: 5.103

10.  Characterization of an antisense transcript spanning the UL81-82 locus of human cytomegalovirus.

Authors:  Mariana Bego; J Maciejewski; S Khaiboullina; G Pari; S St Jeor
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.