Literature DB >> 10875463

The role of chemotherapy in the management of gastric cancer.

R De Vivo1, S Pignata, R Palaia, V Parisi, B Daniele.   

Abstract

Despite a marked decline in the incidence of gastric carcinoma in Western countries, the majority of patients presents with advanced inoperable tumors. In this setting, usually the aim of therapy is palliation, with the exception of chemotherapy administered in the attempt to downstage the tumor and to facilitate potentially curative surgery in patients with locally advanced nonmetastatic disease. This review will focus on the use of chemotherapy for advanced gastric cancer and after curative surgery, providing an overview of future directions for clinical research: preoperative (neoadjuvant) systemic chemotherapy, intraperitoneal treatment, and newer drugs.

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Year:  2000        PMID： 10875463     DOI： 10.1097/00004836-200006000-00004

Source DB:  PubMed          Journal:  J Clin Gastroenterol        ISSN： 0192-0790            Impact factor:   3.062


  5 in total

1.  A phase II study of weekly docetaxel and cisplatin plus oral tegafur/uracil and leucovorin as first-line chemotherapy in patients with locally advanced or metastatic gastric cancer.

Authors:  C-P Li; J-S Chen; L-T Chen; C-J Yen; K-D Lee; W-P Su; P-C Lin; C-H Lu; H-J Tsai; Y Chao
Journal:  Br J Cancer       Date:  2010-10-05       Impact factor: 7.640

2.  An open, multi-centre, phase II clinical trial to evaluate the efficacy and safety of paclitaxel, UFT, and leucovorin in patients with advanced gastric cancer.

Authors:  Y Chao; C P Li; T Y Chao; W C Su; R K Hsieh; M F Wu; K H Yeh; W Y Kao; L T Chen; A L Cheng
Journal:  Br J Cancer       Date:  2006-06-27       Impact factor: 7.640

3.  Benefits of recurrent colonic stent insertion in a patient with advanced gastric cancer with carcinomatosis causing colonic obstruction.

Authors:  Semi Park; Sang Joon Shin; Joong Bae Ahn; Hei-Cheul Jeung; Sun Young Rha; Sang Kil Lee; Hyun Cheol Chung
Journal:  Yonsei Med J       Date:  2009-04-30       Impact factor: 2.759

4.  Phase II study of weekly oxaliplatin and 24-h infusion of high-dose 5-fluorouracil and folinic acid in the treatment of advanced gastric cancer.

Authors:  Y Chao; K H Yeh; C J Chang; L T Chen; T Y Chao; M F Wu; C S Chang; J Y Chang; C Y Chung; W Y Kao; R K Hsieh; A L Cheng
Journal:  Br J Cancer       Date:  2004-08-02       Impact factor: 7.640

5.  DUSP4 promotes doxorubicin resistance in gastric cancer through epithelial-mesenchymal transition.

Authors:  Xing Kang; Minhuan Li; Hao Zhu; Xiaofeng Lu; Ji Miao; Shangce Du; Xuefeng Xia; Wenxian Guan
Journal:  Oncotarget       Date:  2017-10-04
  5 in total

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