Literature DB >> 108744

Inhibition of isolation-induced aggressive behavior with GABA transaminase inhibitors.

J P DaVanzo, M Sydow.   

Abstract

Administration of aminooxyacetic acid (AOAA) and gamma-acetylenic GABA (GAG) resulted in a dose-dependent suppression of aggressive behavior and a concomitant increase in brain GABA. The increase in GABA levels persisted beyond the time when AOAA and GAG exerted an anti-aggressive effect. Brain GABA levels remained significantly elevated over controls for 120 h after a single injection of AOAA and 46 h after a single dose of GAG.

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Year:  1979        PMID： 108744     DOI： 10.1007/bf00426030

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  25 in total

1.  Anticonvulsant properties of amino-oxyacetic acid.

Authors:  J P Davanzo; M E Greig; M A Cronin
Journal:  Am J Physiol       Date:  1961-11

2.  Ataractic suppression of isolation-induced aggressive behavior.

Authors:  C Y YEN; R L STANGER; N MILLMAN
Journal:  Arch Int Pharmacodyn Ther       Date:  1959-12-01

3.  Demonstration of thiosemicarbazide-induced convulsions in rats with elevated brain levels of gamma-aminobutyric acid.

Authors:  C F BAXTER; E ROBERTS
Journal:  Proc Soc Exp Biol Med       Date:  1960-07

4.  Binding of glycine and gamma-aminobutyric acid to synaptosomal fractions of the brains of differentially-housed mice.

Authors:  F V DeFeudis; P Madtes; G Camacho
Journal:  Exp Neurol       Date:  1976-01       Impact factor: 5.330

5.  The effect of 4-amino hex-5-ynoic acid (gamma-acetylenic GABA, gammma-ethynyl GABA) a catalytic inhibitor of GABA transaminase, on brain GABA metabolism in vivo.

Authors:  M J Jung; B Lippert; B W Metcalf; P J Schechter; P Böhlen; A Sjoerdsma
Journal:  J Neurochem       Date:  1977-04       Impact factor: 5.372

6.  Effect of sodium gamma-hydroxybutyrate on isolation-induced aggressivity in mice.

Authors:  N Pöschlová; M Krsiak; R U Ostrovskaya
Journal:  Act Nerv Super (Praha)       Date:  1974-08

Review 7.  Drugs and aggressiveness.

Authors:  L Valzelli
Journal:  Adv Pharmacol       Date:  1967

8.  Effects of centrally active drugs on four models of experimentally-induced aggregession in rodents.

Authors:  R D Sofia
Journal:  Life Sci       Date:  1969-07-01       Impact factor: 5.037

9.  Resistance of androgen-mediated aggressive behavior in mice to flutamide, an antiandrogen.

Authors:  R D Heilman; M Brugmans; F C Greenslade; J P DaVanzo
Journal:  Psychopharmacology (Berl)       Date:  1976-05-05       Impact factor: 4.530

10.  The development of standard stimulus animals for mouse (Mus musculus) aggression testing by means of olfactory bulbectomy.

Authors:  V H Denenberg; E Gaulin-Kremer; R Gandelman; M X Zarrow
Journal:  Anim Behav       Date:  1973-08       Impact factor: 2.844
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  5 in total

1.  Evidence for the involvement of a GABA-mediated inhibition in the hypovolaemia-induced vasopressin release.

Authors:  W Knepel; D Nutto; G Hertting
Journal:  Pflugers Arch       Date:  1980-11       Impact factor: 3.657

2.  Gabaergic modulation of mouse-killing in the rat.

Authors:  A Depaulis; M Vergnes
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

3.  Benzodiazepines and heightened aggressive behavior in rats: reduction by GABA(A)/alpha(1) receptor antagonists.

Authors:  Shannon L Gourley; Joseph F Debold; Wenyuan Yin; James Cook; Klaus A Miczek
Journal:  Psychopharmacology (Berl)       Date:  2004-08-17       Impact factor: 4.530

4.  The influence of isolation and aminooxyacetic acid (AOAA) on GABA in muricidal rats.

Authors:  P Bolin; J P Da Vanzo
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

5.  Effects of sodium n-dipropylacetate, muscimol hydrobromide and (R,S) nipecotic acid amide on isolation-induced aggressive behavior in mice.

Authors:  S Puglisi-Allegra; P Mandel
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530
  5 in total

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