The value of new magnetic resonance techniques in multiple sclerosis.

Cell-specific magnetic resonance imaging, magnetization transfer imaging, proton magnetic resonance spectroscopy and diffusion-weighted imaging have all recently been applied to the study of multiple sclerosis. These techniques can give more accurate and pathologically specific estimates of the multiple sclerosis lesion burden than conventional magnetic resonance. Their extensive application should improve the understanding of the mechanisms leading to multiple sclerosis-related irreversible disability and help in the diagnostic work-out of patients with suspected multiple sclerosis.