Literature DB >> 10871236

Anabolic and destructive mediators in osteoarthritis.

P M van der Kraan1, W B van den Berg.   

Abstract

Osteoarthritis is a joint disease that is characterized by focal degradation of articular cartilage. In addition to the degeneration of articular cartilage, attempts at repair are found in the affected tissue. Cartilage cells (chondrocytes) play a key role, not only in the destructive process, but also in the repair response. It has become apparent that anabolic and catabolic mediators, released from chondrocytes themselves or from other joint cells, drive both destructive and repair activities in the osteoarthritic joint.

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Year:  2000        PMID： 10871236     DOI： 10.1097/00075197-200005000-00007

Source DB:  PubMed          Journal:  Curr Opin Clin Nutr Metab Care        ISSN： 1363-1950            Impact factor:   4.294


  29 in total

1.  Integrin α1β1 differentially regulates cytokine-mediated responses in chondrocytes.

Authors:  R Parekh; M K Lorenzo; S Y Shin; A Pozzi; A L Clark
Journal:  Osteoarthritis Cartilage       Date:  2014-01-11       Impact factor: 6.576

2.  Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro.

Authors:  Salahuddin Ahmed; Naizhen Wang; Bilal Bin Hafeez; Vinay K Cheruvu; Tariq M Haqqi
Journal:  J Nutr       Date:  2005-09       Impact factor: 4.798

3.  sb203580 preconditioning recharges matrix-expanded human adult stem cells for chondrogenesis in an inflammatory environment - A feasible approach for autologous stem cell based osteoarthritic cartilage repair.

Authors:  Ying Zhang; Tyler Pizzute; Jingting Li; Fan He; Ming Pei
Journal:  Biomaterials       Date:  2015-06-20       Impact factor: 12.479

Review 4.  Green tea polyphenol epigallocatechin-3-gallate: inflammation and arthritis. [corrected].

Authors:  Rashmi Singh; Nahid Akhtar; Tariq M Haqqi
Journal:  Life Sci       Date:  2010-05-10       Impact factor: 5.037

5.  Anti-inflammatory and chondroprotective effects of atorvastatin in a cartilage explant model of osteoarthritis.

Authors:  Nitya N Pathak; Madhu C Lingaraju; Venkanna Balaganur; Vinay Kant; Amar S More; Dhirendra Kumar; Dinesh Kumar; Surendra K Tandan
Journal:  Inflamm Res       Date:  2015-01-18       Impact factor: 4.575

6.  Effects of (-)-epigallocatechin-3-gallate on cyclooxygenase 2, PGE(2), and IL-8 expression induced by IL-1beta in human synovial fibroblasts.

Authors:  Guo-Shu Huang; Ching-Ya Tseng; Chian-Her Lee; Sui-Long Su; Herng-Sheng Lee
Journal:  Rheumatol Int       Date:  2009-09-24       Impact factor: 2.631

7.  Bovine lactoferricin is anti-inflammatory and anti-catabolic in human articular cartilage and synovium.

Authors:  Dongyao Yan; Di Chen; Jie Shen; Guozhi Xiao; Andre J van Wijnen; Hee-Jeong Im
Journal:  J Cell Physiol       Date:  2013-02       Impact factor: 6.384

8.  Current nutraceuticals in the management of osteoarthritis: a review.

Authors:  Nahid Akhtar; Tariq M Haqqi
Journal:  Ther Adv Musculoskelet Dis       Date:  2012-06       Impact factor: 5.346

9.  TGF-beta inhibits IL-1beta-activated PAR-2 expression through multiple pathways in human primary synovial cells.

Authors:  Shin-Han Tsai; Ming-Thau Sheu; Yu-Chih Liang; Hsiu-Tan Cheng; Sheng-Shiung Fang; Chien-Ho Chen
Journal:  J Biomed Sci       Date:  2009-10-23       Impact factor: 8.410

10.  In vitro suppression of the MMP-3 gene in normal and cytokine-treated human chondrosarcoma using small interfering RNA.

Authors:  Korakot Nganvongpanit; Patama Chaochird; Puntita Siengdee; Peraphan Pothacharoen; Kasisin Klunklin; Siriwadee Chomdej; Supamit Mekchay; Prachya Kongtaweelert
Journal:  J Orthop Surg Res       Date:  2009-12-24       Impact factor: 2.359
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