Literature DB >> 1087

Detection and partial characterization of lipoprotein lipase in bovine aorta.

L C Henson, M C Schotz.   

Abstract

Extracts of acetone-ether powders of bovine thoracic aorta contain lipase activity which has an alkaline pH maximum (7.8-8.4) and is stimulated 4-10-fold by adding serum or isolated apolipoprotein-glutamate to the assay mixture. Serum activation is completely reversed by isolated apolipoprotein-serine or apolipoprotein-alanine. Lipolysis is strongly inhibited by NaCl (0.5 M) and protamine sulfate (1 mg/ml) and partially inhibited by heparin. Based on these characteristics, the lipase is identified as lipoprotein lipase.

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Year:  1975        PMID： 1087     DOI： 10.1016/0005-2760(75)90031-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  5 in total

Review 1.  The lipoprotein lipase system: new understandings.

Authors:  M H Tan
Journal:  Can Med Assoc J       Date:  1978-03-18       Impact factor: 8.262

2.  Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions.

Authors:  S Ylä-Herttuala; B A Lipton; M E Rosenfeld; I J Goldberg; D Steinberg; J L Witztum
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-15       Impact factor: 11.205

3.  Endogenously produced lipoprotein lipase enhances the binding and cell association of native, mildly oxidized and moderately oxidized low-density lipoprotein in mouse peritoneal macrophages.

Authors:  X Wang; J Greilberger; S Levak-Frank; R Zimmermann; R Zechner; G Jürgens
Journal:  Biochem J       Date:  1999-10-15       Impact factor: 3.857

4.  Changes with starvation in the rat of the lipoprotein lipase activity and hydrolysis of triacylglycerols from triacylglycerol-rich lipoproteins in adipose tissue preparations.

Authors:  M A Lasunción; E Herrera
Journal:  Biochem J       Date:  1983-03-15       Impact factor: 3.857

5.  Effect of platelet-activating factor on lipoprotein lipase and blood lipids.

Authors:  K Mimura; S Yukawa; Y Mori; K Okada; M Mune; O Nishikawa; A Hibino; M Sonobe; T Goto; H Nomoto
Journal:  Lipids       Date:  1991-12       Impact factor: 1.880
  5 in total

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