BACKGROUND AND PURPOSE: In 3D treatment planning of low dose rate brachytherapy of cervical carcinoma the dose in bladder and rectum can be estimated from dose-volume histograms (DVHs). In this study, the influence of inter-observer variation in delineation of bladder and rectum on DVHs and dose at specific bladder and rectum points was investigated. MATERIALS AND METHODS: Three observers delineated bladder and rectum on axial CT images of ten patients. The highest minimum dose in bladder and rectum was determined for, respectively, 2 cm(3) (D(2)) and 5 cm(3) (D(5)), as well as the dose at specific points placed on the bladder and rectum wall. RESULTS: The inter-observer variation in D(2) was 10% (1 average relative SD) in bladder and 11% (1 SD) in rectum. In D(5) the variation was 8% (1 SD) in bladder and 11% in rectum. The variation in the bladder point was 13% (1 SD) and in the rectum point 11% (1 SD). Differences in delineation among the observers were caused by unclear organ boundaries on the CT images. CONCLUSIONS: Taking the inter-observer variation caused by delineation differences into account, dose in bladder and rectum can be determined within an accuracy of about 10% (1 SD).
BACKGROUND AND PURPOSE: In 3D treatment planning of low dose rate brachytherapy of cervical carcinoma the dose in bladder and rectum can be estimated from dose-volume histograms (DVHs). In this study, the influence of inter-observer variation in delineation of bladder and rectum on DVHs and dose at specific bladder and rectum points was investigated. MATERIALS AND METHODS: Three observers delineated bladder and rectum on axial CT images of ten patients. The highest minimum dose in bladder and rectum was determined for, respectively, 2 cm(3) (D(2)) and 5 cm(3) (D(5)), as well as the dose at specific points placed on the bladder and rectum wall. RESULTS: The inter-observer variation in D(2) was 10% (1 average relative SD) in bladder and 11% (1 SD) in rectum. In D(5) the variation was 8% (1 SD) in bladder and 11% in rectum. The variation in the bladder point was 13% (1 SD) and in the rectum point 11% (1 SD). Differences in delineation among the observers were caused by unclear organ boundaries on the CT images. CONCLUSIONS: Taking the inter-observer variation caused by delineation differences into account, dose in bladder and rectum can be determined within an accuracy of about 10% (1 SD).
Authors: M Mukesh; R Benson; R Jena; A Hoole; T Roques; C Scrase; C Martin; G A Whitfield; J Gemmill; S Jefferies Journal: Br J Radiol Date: 2012-08 Impact factor: 3.039
Authors: Antonio L Damato; Kanopkis Townamchai; Michele Albert; Ryan J Bair; Robert A Cormack; Joanne Jang; Arpad Kovacs; Larissa J Lee; Kimberley S Mak; Kristina L Mirabeau-Beale; Kent W Mouw; John G Phillips; Jennifer L Pretz; Andrea L Russo; John H Lewis; Akila N Viswanathan Journal: Int J Radiat Oncol Biol Phys Date: 2014-05-03 Impact factor: 7.038
Authors: Alexandra J Stewart; Robert A Cormack; Hang Lee; Li Xiong; Jorgen L Hansen; Desmond A O'Farrell; Akila N Viswanathan Journal: Int J Radiat Oncol Biol Phys Date: 2008-04-18 Impact factor: 7.038