Literature DB >> 10869139

Split cord malformations--a clinical study of 48 cases.

A Jindal1, A K Mahapatra.   

Abstract

OBJECTIVE: To determine the clinical profile of split cord malformations and to evaluate the results of surgery.
DESIGN: Retrospective.
SUBJECTS: Forty-eight patients of split cord malformation operated during a six years period were studied clinically and radiologically.
RESULTS: The mean age of symptomatic patients was more than that of asymptomatic ones (6.85 years vs 2.03 years). The dorsolumbar and lumbar regions were most frequently involved and in three cases the cervical spine was affected. Weakness of lower limbs (n=37), muscle atrophy (n=23) and gait disturbance were the most common indicators of motor system involvement. The sensory complaints were mainly hypoesthesia (n=16), trophic ulcer (n=4) and autoamputation (n=3). Hypertrichiosis was the most common cutaneous marker present alone or in combination with other markers in 21 cases. MRI, done in all cases, correctly established the diagnosis. Additional lesions causing tethering were seen in 50% cases and were simultaneously treated. Associated Chiari malformation was seen in 12%. Of the 42 symptomatic patients, 21 improved, in 17 (40%) the neurological deficits stabilized and 4 showed deterioration. CSF leak occurred in 4 patients and 3 had wound infections. Among the asymptomatic patients none had neurological deterioration postoperatively.
CONCLUSIONS: Split cord malformations are rare spinal cord disorders. Complete neural axis should be scanned at the first instance to determine associated lesions. Good results can be expected in about 90% patients with minimal complications.

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Year:  2000        PMID: 10869139

Source DB:  PubMed          Journal:  Indian Pediatr        ISSN: 0019-6061            Impact factor:   1.411


  9 in total

1.  Duplicated filum terminale in the absence of split cord malformation: a potential cause of failed detethering procedures.

Authors:  Elias Rizk; Nimer Adeeb; Ahmed E Hussein; R Shane Tubbs; Curtis J Rozzelle; W Jerry Oakes
Journal:  Childs Nerv Syst       Date:  2013-06-07       Impact factor: 1.475

Review 2.  Split cord malformation associated with scoliosis in adults.

Authors:  Rizwan Nazarali; Kristopher Lyon; Joseph Cleveland; David Garrett
Journal:  Proc (Bayl Univ Med Cent)       Date:  2019-03-27

3.  Split cord malformations: an experience of 203 cases.

Authors:  Sumit Sinha; Deepak Agarwal; Ashok Kumar Mahapatra
Journal:  Childs Nerv Syst       Date:  2005-06-03       Impact factor: 1.475

4.  Management of multiple tethering in spinal dysraphism.

Authors:  Raj Kumar; Pallav Garg; Samir Kumar Kalra; Ashok Kumar Mahapatra
Journal:  Childs Nerv Syst       Date:  2010-06-22       Impact factor: 1.475

5.  Comparative study of complex spina bifida and split cord malformation.

Authors:  Raj Kumar; S N Singh; K K Bansal; Vinita Singh
Journal:  Indian J Pediatr       Date:  2005-02       Impact factor: 1.967

6.  Split-cord malformation and tethered cord associated with immature teratoma.

Authors:  Nüket Uzüm; Ayşe Dursun; Kemali Baykaner; Gökhan Kurt
Journal:  Childs Nerv Syst       Date:  2004-04-17       Impact factor: 1.475

7.  Split cord malformation - A study of 300 cases at AIIMS 1990-2006.

Authors:  A K Mahapatra
Journal:  J Pediatr Neurosci       Date:  2011-10

8.  Split cord malformation combined with tethered cord syndrome in an adult.

Authors:  Young Deok Kim; Ji Hoon Sung; Jae Taek Hong; Sang Won Lee
Journal:  J Korean Neurosurg Soc       Date:  2013-10-31

9.  Missing Links Between Genetically Inherited Molecules in Split Cord Malformation and Other Anomaly: A Bench to Bedside Approach.

Authors:  Mayadhar Barik; Pravash R Mishra; Ashok Kumar Mohapatra
Journal:  J Pediatr Neurosci       Date:  2018 Jan-Mar
  9 in total

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