Literature DB >> 10869101

Antioxidants and cancer, part 3: quercetin.

D W Lamson1, M S Brignall.   

Abstract

Quercetin is a flavonoid molecule ubiquitous in nature. A number of its actions make it a potential anti-cancer agent, including cell cycle regulation, interaction with type II estrogen binding sites, and tyrosine kinase inhibition. Quercetin appears to be associated with little toxicity when administered orally or intravenously. Much in vitro and some preliminary animal and human data indicate quercetin inhibits tumor growth. More research is needed to elucidate the absorption of oral doses and the magnitude of the anti-cancer effect.

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Year:  2000        PMID: 10869101

Source DB:  PubMed          Journal:  Altern Med Rev        ISSN: 1089-5159


  106 in total

1.  Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma.

Authors:  Paula Ferrer; Miguel Asensi; Ramón Segarra; Angel Ortega; María Benlloch; Elena Obrador; María T Varea; Gregorio Asensio; Leonardo Jordá; José M Estrela
Journal:  Neoplasia       Date:  2005-01       Impact factor: 5.715

2.  Graphene oxide as selective transporter of flavonols for physiological target DNA: A two-color fluorescence approach.

Authors:  Bidisha Sengupta; Justin Coleman; John Johnson; Manliang Feng
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2019-02-12       Impact factor: 4.098

3.  Role of caffeic acid phenethyl ester on mitomycin C induced clastogenesis: analysis of chromosome aberrations, micronucleus, mitotic index and adenosine deaminase activity in vivo.

Authors:  Ghassan Mohammad Sulaiman
Journal:  J Appl Genet       Date:  2012-03-02       Impact factor: 3.240

4.  Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3).

Authors:  M R Vijayababu; A Arunkumar; P Kanagaraj; P Venkataraman; G Krishnamoorthy; J Arunakaran
Journal:  Mol Cell Biochem       Date:  2006-04-28       Impact factor: 3.396

5.  Quercetin induced apoptosis in association with death receptors and fludarabine in cells isolated from chronic lymphocytic leukaemia patients.

Authors:  M Russo; C Spagnuolo; S Volpe; A Mupo; I Tedesco; G-L Russo
Journal:  Br J Cancer       Date:  2010-07-20       Impact factor: 7.640

6.  The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition.

Authors:  Su-Ni Tang; Chandan Singh; Dara Nall; Daniel Meeker; Sharmila Shankar; Rakesh K Srivastava
Journal:  J Mol Signal       Date:  2010-08-18

Review 7.  Molecular mechanisms of action of quercetin in cancer: recent advances.

Authors:  Dharambir Kashyap; Sonam Mittal; Katrin Sak; Paavan Singhal; Hardeep Singh Tuli
Journal:  Tumour Biol       Date:  2016-07-22

8.  The effect of pretreatment or combined treatment of quercetin on menadione toxicity in rat primary mixed glial cells in vitro.

Authors:  Pinar Oztopcu-Vatan; Selda Kabadere; Ruhi Uyar
Journal:  Cytotechnology       Date:  2009-10-31       Impact factor: 2.058

9.  Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells.

Authors:  Chia-Chen Ko; Yun-Ju Chen; Chih-Ta Chen; Yu-Chih Liu; Fong-Chi Cheng; Kai-Chao Hsu; Lu-Ping Chow
Journal:  J Biol Chem       Date:  2014-06-24       Impact factor: 5.157

10.  Establishment of a P-glycoprotein substrate screening model and its preliminary application.

Authors:  Yi Wang; Jiang Cao; Su Zeng
Journal:  World J Gastroenterol       Date:  2004-05-01       Impact factor: 5.742

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