Literature DB >> 10868715

Characterization of the inspiratory manoeuvre when asthmatics inhale through a Turbohaler pre- and post-counselling in a community pharmacy.

G M Hawksworth1, L James, H Chrystyn.   

Abstract

Dose emission from a Turbohaler has been shown to be dependent on the rate of inhalation, with an optimal flow of 60 l min(-1) recommended. Some patients may need counselling to achieve this fast inhalation. Inhalation rate profiles of 24 asthmatics were measured when they inhaled through a placebo Turbohaler. The setting was a community pharmacy when the asthmatics came to collect their next supply of medication. Profiles were measured before and after counselling on how to use the Turbohaler. The mean (SD) peak inhalation rate through the Turbohaler pre- and post-counselling was 48.0 (16.8) and 54.7 (17.6) l min(-1), and their inspiratory volume was 1.75 (0.68) and 1.94 (0.62) l, respectively. Their mean (SD) percent predicted FEV1 was 57.0 (18.9)%. After counselling, 12 patients achieved an inhalation rate of > 60 l min(-1) and a further four obtained > 55 l min(-1). Emphasis should be placed on counselling patients prescribed all types of inhaled devices rather than concentrating on metered dose inhalers.

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Year:  2000        PMID: 10868715     DOI: 10.1053/rmed.1999.0768

Source DB:  PubMed          Journal:  Respir Med        ISSN: 0954-6111            Impact factor:   3.415


  8 in total

1.  Ideal Particle Sizes for Inhaled Steroids Targeting Vocal Granulomas: Preliminary Study Using Computational Fluid Dynamics.

Authors:  Elizabeth L Perkins; Saikat Basu; Guilherme J M Garcia; Robert A Buckmire; Rupali N Shah; Julia S Kimbell
Journal:  Otolaryngol Head Neck Surg       Date:  2017-11-21       Impact factor: 3.497

2.  The effect of using simulation for training pharmacy students on correct device technique.

Authors:  Iman A Basheti
Journal:  Am J Pharm Educ       Date:  2014-12-15       Impact factor: 2.047

3.  Reduced Peak Inspiratory Effort through the Diskus((R)) and the Turbuhaler((R)) due to Mishandling is Common in Clinical Practice.

Authors:  Andrea S Melani; Letizia S Bracci; Marcello Rossi
Journal:  Clin Drug Investig       Date:  2005       Impact factor: 2.859

4.  Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study.

Authors:  Wahida Azouz; Philip Chetcuti; Harold Hosker; Dinesh Saralaya; Henry Chrystyn
Journal:  BMC Pulm Med       Date:  2015-05-01       Impact factor: 3.317

Review 5.  The Confusing World of Dry Powder Inhalers: It Is All About Inspiratory Pressures, Not Inspiratory Flow Rates.

Authors:  Andrew R Clark; Jeffry G Weers; Rajiv Dhand
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2019-10-31       Impact factor: 2.849

6.  Patients with asthma or chronic obstructive pulmonary disease (COPD) can generate sufficient inspiratory flows via Easyhaler® dry powder inhaler: a pooled analysis of two randomized controlled trials.

Authors:  L Pekka Malmberg; Anna S Pelkonen; Ville Vartiainen; Mikko Vahteristo; Satu Lähelmä; Rain Jõgi
Journal:  J Thorac Dis       Date:  2021-02       Impact factor: 3.005

Review 7.  The Diskus: a review of its position among dry powder inhaler devices.

Authors:  H Chrystyn
Journal:  Int J Clin Pract       Date:  2007-06       Impact factor: 2.503

8.  Switching patients from other inhaled corticosteroid devices to the Easyhaler(®): historical, matched-cohort study of real-life asthma patients.

Authors:  David Price; Vicky Thomas; Julie von Ziegenweidt; Shuna Gould; Catherine Hutton; Christine King
Journal:  J Asthma Allergy       Date:  2014-04-10
  8 in total

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