Literature DB >> 10868356

Treatment approaches for congenital pseudarthrosis of tibia: results of the EPOS multicenter study. European Paediatric Orthopaedic Society (EPOS).

F Grill1, G Bollini, P Dungl, J Fixsen, F Hefti, E Ippolito, B Romanus, C Tudisco, S Wientroub.   

Abstract

This study was designed to analyze the different therapeutic methods used by European Paediatric Orthopaedic Society members from 13 countries for congenital pseudarthrosis of tibia. The treatment data of 340 patients who underwent 1287 procedures for this condition were analyzed. The essential findings were that the method of choice needed to approach the biological problem with the aims of: (1) resecting the pseudarthrosis to provide stability, the basic requirement for bony consolidation; (2) correcting length discrepancy and axial deformity; (3) achieving fusion; and (4) solving the additional problems around the main deformity such as alignment, leg length discrepancy and ankle valgus. The Ilizarov technique emerged as being the optimal method, having the highest rate of fusion (75.5%) of pseudarthrosis and rate of success in correction of the additional deformities. There was also consensus that surgery should be avoided before the third year of life.

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Year:  2000        PMID: 10868356     DOI: 10.1097/01202412-200004000-00002

Source DB:  PubMed          Journal:  J Pediatr Orthop B        ISSN: 1060-152X            Impact factor:   1.041


  37 in total

1.  Periosteal grafting for congenital pseudarthrosis of the tibia: a preliminary report.

Authors:  Ahmed M Thabet; Dror Paley; Mehmet Kocaoglu; Levent Eralp; John E Herzenberg; Omer Naci Ergin
Journal:  Clin Orthop Relat Res       Date:  2008-10-25       Impact factor: 4.176

2.  Bone morphogenetic protein-2 for the treatment of congenital pseudarthrosis of the tibia or persistent tibial nonunion in children and adolescents: A retrospective study with a minimum 2-year follow-up.

Authors:  Tim N Hissnauer; Norbert Stiel; Kornelia Babin; Martin Rupprecht; Michael Hoffmann; Johannes M Rueger; Ralf Stuecker; Alexander S Spiro
Journal:  J Mater Sci Mater Med       Date:  2017-02-17       Impact factor: 3.896

Review 3.  [Malformations of the lower extremities].

Authors:  F Hefti
Journal:  Orthopade       Date:  2008-04       Impact factor: 1.087

4.  Preliminary experience with the combined use of recombinant bone morphogenetic protein and bisphosphonates in the treatment of congenital pseudarthrosis of the tibia.

Authors:  Oliver Birke; Aaron Schindeler; Manoj Ramachandran; Chris T Cowell; Craig F Munns; Michael Bellemore; David G Little
Journal:  J Child Orthop       Date:  2010-10-21       Impact factor: 1.548

Review 5.  Ilizarov treatment of congenital pseudarthrosis of the tibia: a multi-targeted approach using the Ilizarov technique.

Authors:  In Ho Choi; Tae-Joon Cho; Hyuk Ju Moon
Journal:  Clin Orthop Surg       Date:  2011-02-15

6.  Relationship between postoperative complications and fibular integrity in congenital pseudarthrosis of the tibia in children.

Authors:  Yao-Xi Liu; Hai-Bo Mei; Guang-Hui Zhu; Rong-Guo He; Kun Liu; Jin Tang; Jiang-Yan Wu; Wei-Hua Ye; Xin Hu; Qian Tan; An Yan; Sheng-Xiang Huang; Xiao-Qian Tan; Ting Lei
Journal:  World J Pediatr       Date:  2016-12-23       Impact factor: 2.764

7.  Congenital pseudarthrosis of the tibia: the results of an evolving protocol of management.

Authors:  N Nicolaou; A Ghassemi; R A Hill
Journal:  J Child Orthop       Date:  2013-06-12       Impact factor: 1.548

8.  Induced membrane technique for the treatment of congenital pseudarthrosis of the tibia: preliminary results of five cases.

Authors:  Stéphanie Pannier; Zagorka Pejin; Caroline Dana; Alain Charles Masquelet; Christophe Glorion
Journal:  J Child Orthop       Date:  2013-10-08       Impact factor: 1.548

9.  Epidemiology and treatment outcome of congenital pseudarthrosis of the tibia.

Authors:  Joachim Horn; Harald Steen; Terje Terjesen
Journal:  J Child Orthop       Date:  2013-01-18       Impact factor: 1.548

10.  Health-related quality of life measures in genetic disorders: an outcome variable for consideration in clinical trials.

Authors:  David A Stevenson; John C Carey
Journal:  Am J Med Genet C Semin Med Genet       Date:  2009-08-15       Impact factor: 3.908

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