| Literature DB >> 10867808 |
U Herrlinger1, K Klingel, R Meyermann, R Kandolf, E Kaiserling, R D Kortmann, A Melms, M Skalej, J Dichgans, M Weller.
Abstract
A 66-year-old woman treated for ocular myasthenia gravis with azathioprine for 12 years presented with a left fronto-parietal mass. Histology revealed primary Hodgkin's lymphoma of the central nervous system with CD30, Epstein-Barr virus (EBV) latent membrane protein and CD20-positive, CD45 (LCA)-negative Reed-Sternberg cells surrounded by T cells. Moreover, EBV-encoded RNA-1 (EBER-1) sequences and a monoclonal rearrangement of the immunoglobulin heavy chain CDR2 locus were detected.Entities:
Mesh:
Year: 2000 PMID: 10867808 DOI: 10.1007/s004010051185
Source DB: PubMed Journal: Acta Neuropathol ISSN: 0001-6322 Impact factor: 17.088