| Literature DB >> 10867214 |
M Lehtovirta1, M P Laakso, G B Frisoni, H Soininen.
Abstract
The epsilon 4 allele of apolipoprotein E is a risk factor for Alzheimer's disease, but also a modulator of its clinical picture. In this paper, recent research in neuroimaging of aging and Alzheimer's disease in relation to apolipoprotein E is reviewed, emphasizing the advances but also the controversies. Further, the possible clinicopathological implications of these findings are discussed.Entities:
Mesh:
Substances:
Year: 2000 PMID: 10867214 DOI: 10.1016/s0197-4580(00)00120-2
Source DB: PubMed Journal: Neurobiol Aging ISSN: 0197-4580 Impact factor: 4.673