| Literature DB >> 10866382 |
A K Bakkestuen1, L L Gundersen, G Langli, F Liu, J M Nolsøe.
Abstract
9-Benzylpurines with a variety of substituents in the 2-, 6- and/or 8-position have been prepared and screened for antimycobacterial effects. High inhibitory activity against Mycobacterium tuberculosis was found for 9-benzylpurines carrying a phenylethynyl-, trans-styryl or aryl substituents in the 6-position and generally chlorine in the 2-position tends to increase activity.Entities:
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Year: 2000 PMID： 10866382 DOI： 10.1016/s0960-894x(00)00188-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823