Literature DB >> 10866381

Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists.

B L Chenard1, F S Menniti, M J Pagnozzi, K D Shenk, F E Ewing, W M Welch.   

Abstract

Quinazolin-4-one derivatives of methaqualone substituted at C-2 define a new class of noncompetitive antagonists at AMPA receptors.

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Year:  2000        PMID: 10866381     DOI: 10.1016/s0960-894x(00)00216-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

Review 1.  Ionotropic and metabotropic glutamate receptor structure and pharmacology.

Authors:  James N C Kew; John A Kemp
Journal:  Psychopharmacology (Berl)       Date:  2005-02-25       Impact factor: 4.530

2.  5'-Methyl-4'-oxo-7'-phenyl-3',4'-dihydro-1'H-spiro-[cyclo-hexane-1,2'-quinazoline]-8'-carbonitrile.

Authors:  Jianhong Tang; Daxin Shi; Liupan Yan; Xuan Liu; Jiarong Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-06-18

3.  Electro-oxidative cyclization: access to quinazolinones via K2S2O8 without transition metal catalyst and base.

Authors:  Yongzhi Hu; Huiqing Hou; Ling Yu; Sunying Zhou; Xianghua Wu; Weiming Sun; Fang Ke
Journal:  RSC Adv       Date:  2021-09-24       Impact factor: 4.036

  3 in total

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