Literature DB >> 1086611

The effect of central chemical sympathectomy on the oxygen uptake; anaerobic glycolysis and lactic acid dehydrogenase activity in the retina of white rats.

S M Pojda, R Brus.   

Abstract

Male Wistar rats were injected intraventricularly with two doses of 250 mcg of 6-hydroxydopamine (6-OHDA) in two consecutive days. Two weeks later the oxygen uptake, anaerobic glycolysis and lactic acid dehydrogenase (LDH) activity in the retina were determined. The decrease of oxygen uptake (-28%), anaerobic glycolysis (-31%) and LDH activity (-12%) in rats treated with 6-OHDA in comparison to control animals was found. The possible role of the adrenergic system in regulation of the metabolism of the retina is discussed.

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Year:  1976        PMID： 1086611     DOI： 10.1007/bf01028537

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN： 0065-6100


  11 in total

1.  Metabolism of the developing retina. I. Aerobic and anaerobic glycolysis in the developing rat retina.

Authors:  C GRAYMORE
Journal:  Br J Ophthalmol       Date:  1959-01       Impact factor: 4.638

2.  Lactic dehydrogenase activity in blood.

Authors:  F WROBLEWSKI; J S LADUE
Journal:  Proc Soc Exp Biol Med       Date:  1955-10

3.  Swelling of the rat retina induced by metabolic inhibition.

Authors:  C GRAYMORE
Journal:  Br J Ophthalmol       Date:  1958-06       Impact factor: 4.638

4.  Interaction between 6-hydroxydopamine and rhodopsin in vivo in the rat retina.

Authors:  S F Pong; L T Graham
Journal:  Experientia       Date:  1974-08-15

5.  Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine.

Authors:  H Thoenen; J P Tranzer
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1968

6.  Effect of 6-hydroxydopamine on dark adaptation in the rat retina.

Authors:  S F Pong; L T Graham
Journal:  Life Sci       Date:  1973-07-01       Impact factor: 5.037

7.  Behaviour of rats and biogenic amine level in brain after 6-hydroxy-dopamine.

Authors:  Z S Herman; K Kmieciak-Kolada; R Brus
Journal:  Psychopharmacologia       Date:  1972

8.  Effect of 6-hydroxydopamine on brain norepinephrine and dopamine evidence for selective degeneration of catecholamine neurons.

Authors:  G R Breese; T D Traylor
Journal:  J Pharmacol Exp Ther       Date:  1970-09       Impact factor: 4.030

9.  Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain.

Authors:  N J Uretsky; L L Iversen
Journal:  J Neurochem       Date:  1970-02       Impact factor: 5.372

10.  Anterior segment chemical sympathectomy by 6-hydroxy-dopamine. I. Effect on intraocular pressure and facility of outflow.

Authors:  M G Holland; J L Mims
Journal:  Invest Ophthalmol       Date:  1971-02
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  1 in total

1.  Parkinson's disease, lights and melanocytes: looking beyond the retina.

Authors:  Gregory L Willis; Cleo Moore; Stuart Maxwell Armstrong
Journal:  Sci Rep       Date:  2014-01-29       Impact factor: 4.379
  1 in total

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