Literature DB >> 10865855

Effect of leptin in platelet and endothelial cells. Obesity and arterial thrombosis.

I Maruyama1, M Nakata, K Yamaji.   

Abstract

We demonstrated that leptin showed effects on both platelets and endothelial cells through its functional receptor. These effects are the vector to inducing thrombotic tendency. Leptin concentrations used in our experiments correspond to that of leptin in the circulation of obese individuals. Thus we suggest that increased leptin may act as a risk factor for thrombosis in obese individuals.

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Year:  2000        PMID： 10865855     DOI： 10.1111/j.1749-6632.2000.tb06330.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  8 in total

1.  The unfolding tale of leptin.

Authors:  H Jeet Singh
Journal:  Malays J Med Sci       Date:  2001-07

2.  Race-ethnic differences in adipokine levels: the Study of Women's Health Across the Nation (SWAN).

Authors:  Unab I Khan; Dan Wang; Maryfran R Sowers; Peter Mancuso; Susan A Everson-Rose; Philipp E Scherer; Rachel P Wildman
Journal:  Metabolism       Date:  2012-03-22       Impact factor: 8.694

3.  Leptin receptor-induced STAT3-independent signaling pathways are protective against atherosclerosis in a murine model of obesity and hyperlipidemia.

Authors:  Wei Luo; Peter F Bodary; Yuechun Shen; Kevin J Wickenheiser; Miina K Ohman; Chiao Guo; Kristina L Bahrou; Martin G Myers; Daniel T Eitzman
Journal:  Atherosclerosis       Date:  2010-10-16       Impact factor: 5.162

4.  Adipokines, adiposity, and vasomotor symptoms during the menopause transition: findings from the Study of Women's Health Across the Nation.

Authors:  Rebecca C Thurston; Yuefang Chang; Peter Mancuso; Karen A Matthews
Journal:  Fertil Steril       Date:  2013-06-10       Impact factor: 7.329

Review 5.  Immune and inflammatory mechanisms of atherosclerosis (*).

Authors:  Elena Galkina; Klaus Ley
Journal:  Annu Rev Immunol       Date:  2009       Impact factor: 28.527

Review 6.  Coagulation and fibrinolysis abnormalities in obesity.

Authors:  G De Pergola; N Pannacciulli
Journal:  J Endocrinol Invest       Date:  2002-11       Impact factor: 4.256

7.  A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice.

Authors:  Adam Miszta; Anna K Kopec; Asmita Pant; Lori A Holle; James R Byrnes; Daniel A Lawrence; Kirk C Hansen; Matthew J Flick; James P Luyendyk; Bas de Laat; Alisa S Wolberg
Journal:  Blood       Date:  2020-05-07       Impact factor: 22.113

8.  Influence of acute hyperlipidemia to adipocyte-derived hormones in lean normotensive and subjects with metabolic syndrome.

Authors:  Heno F Lopes; Richard L Klein; W Timothy Garvey; Theodore Goodfriend; Brent M Egan
Journal:  Diabetol Metab Syndr       Date:  2014-12-02       Impact factor: 3.320
  8 in total

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