| Literature DB >> 10865459 |
F Traore, R Faure, E Ollivier, M Gasquet, N Azas, L Debrauwer, A Keita, P Timon-David, G Balansard.
Abstract
Two new triterpenoid saponins, glinosides A and B, isolated from the aerial parts of Glinus oppositifolius, have been characterized by 1D, 2D, NMR and high-resolution mass spectral (HRMS) techniques. Their structures were established respectively as 16-O-(beta-arabinopyranosyl)-3-oxo-12,16 beta,21 beta,22-tetrahydroxyhopane for glinoside A and 16-O-(beta-arabinopyranosyl)-3-oxo-12,16 beta,22-trihydroxyhopane for glinoside B. Results presented evidence that fractions had a better antiplasmodial activity (IC50 = 31.80 micrograms/ml) than pure glinoside A (IC50 = 42.30 micrograms/ml).Entities:
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Year: 2000 PMID: 10865459 DOI: 10.1055/s-2000-8551
Source DB: PubMed Journal: Planta Med ISSN: 0032-0943 Impact factor: 3.352