Literature DB >> 10865457

Agelasine F from a Philippine Agelas sp. sponge exhibits in vitro antituberculosis activity.

G C Mangalindan, M T Talaue, L J Cruz, S G Franzblau, L B Adams, A D Richardson, C M Ireland, G P Concepcion.   

Abstract

Marine sponge samples were collected in Baler, Aurora, Philippines, and extracts were tested for in vitro antituberculosis activity. An orange Agelas sp. sponge yielded the known compound, agelasine F, which inhibited some drug resistant strains of Mycobacterium tuberculosis in vitro at concentrations as low as 3.13 micrograms/ml. Activity against M. tuberculosis residing within macrophages required concentrations of 13-22 micrograms/ml which was below the IC50 for Vero cells (34 micrograms/ml).

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10865457     DOI： 10.1055/s-2000-8554

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  9 in total

Review 1.  Marine pharmacology in 2000: marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antituberculosis, and antiviral activities; affecting the cardiovascular, immune, and nervous systems and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Mark T Hamann
Journal:  Mar Biotechnol (NY)       Date:  2003-11-03       Impact factor: 3.619

2.  Discovery and characterization of the tuberculosis drug lead ecumicin.

Authors:  Wei Gao; Jin-Yong Kim; Shao-Nong Chen; Sang-Hyun Cho; Jongkeun Choi; Birgit U Jaki; Ying-Yu Jin; David C Lankin; Ji-Ean Lee; Sun-Young Lee; James B McAlpine; José G Napolitano; Scott G Franzblau; Joo-Won Suh; Guido F Pauli
Journal:  Org Lett       Date:  2014-11-19       Impact factor: 6.005

3.  Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel .

Authors:  George R Pettit; Yuping Tang; Qingwen Zhang; Gregory T Bourne; Christoph A Arm; John E Leet; John C Knight; Robin K Pettit; Jean-Charles Chapuis; Dennis L Doubek; Franklin J Ward; Christine Weber; John N A Hooper
Journal:  J Nat Prod       Date:  2013-02-14       Impact factor: 4.050

4.  The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo.

Authors:  Wei Gao; Jin-Yong Kim; Jeffrey R Anderson; Tatos Akopian; Seungpyo Hong; Ying-Yu Jin; Olga Kandror; Jong-Woo Kim; In-Ae Lee; Sun-Young Lee; James B McAlpine; Surafel Mulugeta; Suhair Sunoqrot; Yuehong Wang; Seung-Hwan Yang; Tae-Mi Yoon; Alfred L Goldberg; Guido F Pauli; Joo-Won Suh; Scott G Franzblau; Sanghyun Cho
Journal:  Antimicrob Agents Chemother       Date:  2014-11-24       Impact factor: 5.191

Review 5.  Marine Alkylpurines: A Promising Group of Bioactive Marine Natural Products.

Authors:  Pablo A García; Elena Valles; David Díez; María-Ángeles Castro
Journal:  Mar Drugs       Date:  2018-01-01       Impact factor: 5.118

6.  Action of Dicumarol on Glucosamine-1-Phosphate Acetyltransferase of GlmU and Mycobacterium tuberculosis.

Authors:  Xiuyan Han; Changming Chen; Qiulong Yan; Liqiu Jia; Ayaz Taj; Yufang Ma
Journal:  Front Microbiol       Date:  2019-08-20       Impact factor: 5.640

7.  Identification of Antimycobacterial Natural Products from a Library of Marine Invertebrate Extracts.

Authors:  Kojo Sekyi Acquah; Denzil R Beukes; Ronnett Seldon; Audrey Jordaan; Suthananda N Sunassee; Digby F Warner; David W Gammon
Journal:  Medicines (Basel)       Date:  2022-01-28

Review 8.  Secondary metabolites from marine sponges of the genus Agelas: a comprehensive update insight on structural diversity and bioactivity.

Authors:  Mei-Jun Chu; Meng Li; He Ma; Ping-Lin Li; Guo-Qiang Li
Journal:  RSC Adv       Date:  2022-03-09       Impact factor: 3.361

Review 9.  Terpenyl-purines from the sea.

Authors:  Marina Gordaliza
Journal:  Mar Drugs       Date:  2009-12-23       Impact factor: 5.118
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.