Literature DB >> 10865450

Assessment of antimycobacterial activity of a series of mainly marine derived natural products.

G M König1, A D Wright, S G Franzblau.   

Abstract

A series of mainly marine derived natural products were tested for their activities against Mycobacterium tuberculosis and M. avium. Of the thirty-nine compounds tested fifteen demonstrated minimum inhibition concentrations (MICs) of 32 micrograms/ml or less, and eleven had MICs of 16 micrograms/ml or less. The most active compound found in this study was the sponge derived metabolite axisonitrile-3 (MIC 2 micrograms/ml).

Entities:  

Mesh:

Substances:

Year:  2000        PMID: 10865450     DOI: 10.1055/s-2000-8534

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  12 in total

Review 1.  Marine pharmacology in 2000: marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antituberculosis, and antiviral activities; affecting the cardiovascular, immune, and nervous systems and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Mark T Hamann
Journal:  Mar Biotechnol (NY)       Date:  2003-11-03       Impact factor: 3.619

Review 2.  Bioactive Compounds from Marine Heterobranchs.

Authors:  Conxita Avila; Carlos Angulo-Preckler
Journal:  Mar Drugs       Date:  2020-12-21       Impact factor: 5.118

3.  Quinones and halogenated monoterpenes of algal origin show anti-proliferative effects against breast cancer cells in vitro.

Authors:  Jo-Anne de la Mare; Jessica C Lawson; Maynard T Chiwakata; Denzil R Beukes; Adrienne L Edkins; Gregory L Blatch
Journal:  Invest New Drugs       Date:  2012-01-17       Impact factor: 3.850

Review 4.  Antibacterials from the sea.

Authors:  Chambers C Hughes; William Fenical
Journal:  Chemistry       Date:  2010-11-08       Impact factor: 5.236

5.  Anticoagulation and antiplatelet effects of a dolastane diterpene isolated from the marine brown alga Canistrocarpus cervicornis.

Authors:  Laura de Andrade Moura; Everson Miguel Bianco; Renato Crespo Pereira; Valéria Laneuville Teixeira; André Lopes Fuly
Journal:  J Thromb Thrombolysis       Date:  2011-02       Impact factor: 2.300

6.  2-methoxylated fatty acids in marine sponges: defense mechanism against mycobacteria?

Authors:  Néstor M Carballeira; Heidyleen Cruz; Cecil D Kwong; Baojie Wan; Scott Franzblau
Journal:  Lipids       Date:  2004-07       Impact factor: 1.880

7.  Derivatives of usnic acid inhibit broad range of influenza viruses and protect mice from lethal influenza infection.

Authors:  A A Shtro; V V Zarubaev; O A Luzina; D N Sokolov; N F Salakhutdinov
Journal:  Antivir Chem Chemother       Date:  2016-03-27

8.  Nitric Oxide Production Inhibition and Anti-Mycobacterial Activity of Extracts and Halogenated Sesquiterpenes from the Brazilian Red Alga Laurencia Dendroidea J. Agardh.

Authors:  Thatiana Lopes Biá Ventura; Fernanda Lacerda da Silva Machado; Marlon Heggdorne de Araujo; Lísia Mônica de Souza Gestinari; Carlos Roland Kaiser; Francisco de Assis Esteves; Elena B Lasunskaia; Angélica Ribeiro Soares; Michelle Frazão Muzitano
Journal:  Pharmacogn Mag       Date:  2015-10       Impact factor: 1.085

9.  Dolabelladienols A-C, new diterpenes isolated from Brazilian brown alga Dictyota pfaffii.

Authors:  Alonso Pardo-Vargas; Ingrid de Barcelos Oliveira; Paulo Roberto Soares Stephens; Claudio Cesar Cirne-Santos; Izabel Christina Nunes de Palmer Paixão; Freddy Alejandro Ramos; Carlos Jiménez; Jaime Rodríguez; Jackson Antonio Lamounier Camargos Resende; Valeria Laneuville Teixeira; Leonardo Castellanos
Journal:  Mar Drugs       Date:  2014-07-23       Impact factor: 5.118

Review 10.  Marine natural products and their potential applications as anti-infective agents.

Authors:  Marwa Donia; Mark T Hamann
Journal:  Lancet Infect Dis       Date:  2003-06       Impact factor: 25.071

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.