Literature DB >> 10864618

Injections of botulinum toxin A into the salivary glands improve sialorrhoea in amyotrophic lateral sclerosis.

R Giess1, M Naumann, E Werner, R Riemann, M Beck, I Puls, C Reiners, K V Toyka.   

Abstract

Sialorrhoea is a socially disabling problem in bulbar amyotrophic lateral sclerosis (ALS). Botulinum toxin A (BoNT/A) was injected into the salivary glands in five patients with bulbar ALS and sialorrhoea. The effect of BoNT/A was measured by the number of paper handkerchiefs used each day and by salivary gland scintigraphy. BoNT/A ameliorated sialorrhoea and quality of life without major adverse effects. BoNT/A may be a relatively safe and effective treatment for sialorrhoea in selected patients.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10864618      PMCID： PMC1736996          DOI： 10.1136/jnnp.69.1.121

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  28 in total

Review 1.  Management of motor neurone disease.

Authors:  R S Howard; R W Orrell
Journal:  Postgrad Med J       Date:  2002-12       Impact factor: 2.401

Review 2.  Botulinum toxin in clinical practice.

Authors:  J Jankovic
Journal:  J Neurol Neurosurg Psychiatry       Date:  2004-07       Impact factor: 10.154

Review 3.  Evidence for the effectiveness of botulinum toxin for sialorrhoea.

Authors:  D D Truong; R Bhidayasiri
Journal:  J Neural Transm (Vienna)       Date:  2008-02-04       Impact factor: 3.575

Review 4.  Amyotrophic lateral sclerosis: update for family physicians.

Authors:  Christen L Shoesmith; Michael J Strong
Journal:  Can Fam Physician       Date:  2006-12       Impact factor: 3.275

5.  Botulinum toxin therapy: its use for neurological disorders of the autonomic nervous system.

Authors:  Dirk Dressler
Journal:  J Neurol       Date:  2012-08-10       Impact factor: 4.849

Review 6.  Symptom Management and End-of-Life Care in Amyotrophic Lateral Sclerosis.

Authors:  Carlayne E Jackson; April L McVey; Stacy Rudnicki; Mazen M Dimachkie; Richard J Barohn
Journal:  Neurol Clin       Date:  2015-11       Impact factor: 3.806

Review 7.  The use of botulinum toxin injections to manage drooling in amyotrophic lateral sclerosis/motor neurone disease: a systematic review.

Authors:  Nina Squires; Miles Humberstone; Adrian Wills; Antony Arthur
Journal:  Dysphagia       Date:  2014-05-22       Impact factor: 3.438

Review 8.  [Treatment of sialorrhea with botulinum toxin: an overview].

Authors:  J Hagenah; K G Kahl; S Steinlechner; R Lencer; C Klein
Journal:  Nervenarzt       Date:  2005-04       Impact factor: 1.214

Review 9.  [Pharmacological strategies for clozapine-induced hypersalivation: treatment with botulinum toxin B in one patient and review of the literature].

Authors:  K G Kahl; P Trillenberg; A Kordon; R Lencer; C Klein; J Hagenah
Journal:  Nervenarzt       Date:  2005-02       Impact factor: 1.214

10.  Botulinum toxin type-B improves sialorrhea and quality of life in bulbaronset amyotrophic lateral sclerosis.

Authors:  João Costa; Maria Luz Rocha; Joaquim Ferreira; Teresinha Evangelista; Miguel Coelho; Mamede de Carvalho
Journal:  J Neurol       Date:  2008-02-19       Impact factor: 4.849
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.