Literature DB >> 1086461

Ionic mechanism of inotropic effect of prostaglandin E1 on frog atrial muscle.

J Mironneau, A Grosset.   

Abstract

Prostaglandin E1 increases the amplitude and duration of cardiac action potential and exerts a positive inotropic effect on the frog heart. In voltage-clamp experiments, prostaglandin E1 increases both, the slow inward current and the delayed outward as well as the two components of the heart contraction. These results imply that calcium influx and the release of intracellular calcium are involved in the inotropic action of prostaglandin E1.

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Year:  1976        PMID： 1086461     DOI： 10.1007/bf02486564

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  13 in total

1.  The influence of non-uniformity on the analysis of potassium currents in atrial muscle.

Authors:  H F Brown; D Noble; S J Noble
Journal:  J Physiol       Date:  1975-02       Impact factor: 5.182

2.  Calcium conductance and tension in mammalian ventricular muscle.

Authors:  W Trautwein; T F McDonald; O Tripathi
Journal:  Pflugers Arch       Date:  1975       Impact factor: 3.657

3.  THE SPECIES SPECIFICITY OF PROSTAGLANDIN E 1 EFFECTS ON ISOLATED HEART.

Authors:  F BERTI; R LENTATI; M M USARDI
Journal:  Med Pharmacol Exp Int J Exp Med       Date:  1965

4.  An assessment of the double sucrose-gap voltage clamp technique as applied to frog atrial muscle.

Authors:  M Tarr; J W Trank
Journal:  Biophys J       Date:  1974-09       Impact factor: 4.033

5.  The influence of adrenergic and some other cardioactive drugs on electric activity of the isolated frog atrium.

Authors:  V Smejkal; O Rougier; D Garnier
Journal:  Physiol Bohemoslov       Date:  1970

6.  [Influence of adrenergic substances and prostaglandin E 1 on the spontaneous electrical activity of the rabbit auricle].

Authors:  J Mironneau; V Smejkal; C Ojeda
Journal:  C R Seances Soc Biol Fil       Date:  1969

7.  Mechanical activity and ionic currents in frog atrial trabeculae.

Authors:  C Léoty; G Raymond
Journal:  Pflugers Arch       Date:  1972       Impact factor: 3.657

Review 8.  The prostaglandins: a family of biologically active lipids.

Authors:  S Bergström; L A Carlson; J R Weeks
Journal:  Pharmacol Rev       Date:  1968-03       Impact factor: 25.468

9.  Existence and role of a slow inward current during the frog atrial action potential.

Authors:  O Rougier; G Vassort; D Garnier; Y M Gargouil; E Coraboeuf
Journal:  Pflugers Arch       Date:  1969       Impact factor: 3.657

10.  Prostaglandins, myometrial 'enhancement' and calcium.

Authors:  E M Eagling; H Lovell; V R Pickles
Journal:  J Physiol       Date:  1971-03       Impact factor: 5.182
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  3 in total

1.  Pharmacological modification of mechanical and electrical responses of frog heart to thrombin.

Authors:  F Markwardt; T Franke; E Glusa; B Nilius
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-04       Impact factor: 3.000

2.  Release of prostaglandins from the isolated frog ventricle and associated changes in endogenous cyclic nucleotide levels.

Authors:  F W Flitney; J Singh
Journal:  J Physiol       Date:  1980-07       Impact factor: 5.182

3.  Inotropic actions of eicosanoids.

Authors:  K Schrör; T Hohlfeld
Journal:  Basic Res Cardiol       Date:  1992 Jan-Feb       Impact factor: 17.165
  3 in total

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