Literature DB >> 1086310

Rosette inhibition test in chronic liver disease.

F Salerno, S R Fargion, M D Cappellini, G Fiorelli, N Dioguardi.   

Abstract

A role has recently been assigned to cell-mediated immunity in chronic liver diseases in addition to the well-known alterations of humoral immunity. We now report the results of the rosette inhibition test for the evaluation of T-lymphocyte "sensitization" in patients with different chronic liver disorders. A cell-mediated immune reaction was found in 81% of patients with chronic active hepatitis and in 71% with primary biliary cirrhosis, whereas patients with chronic persistent hepatitis showed no reaction. The correlation with the incidence of hepatitis B antigen showed that T-lymphocyte sensitization was more frequent in the group of HB-positive patients. Finally, improvement of the test was observed in four out of nine patients given immunosuppressive treatment.

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Year:  1976        PMID： 1086310      PMCID： PMC476178          DOI： 10.1136/jcp.29.9.778

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  19 in total

1.  IMMUNOCYTOCHEMICAL AND SEROLOGIC OBSERVATIONS IN PRIMARY BILIARY CIRRHOSIS.

Authors:  F PARONETTO; F SCHAFFNER; H POPPER
Journal:  N Engl J Med       Date:  1964-11-26       Impact factor: 91.245

2.  Lymphocyte stimulation and chronic liver disease.

Authors:  H Tobias; A P Safran; F Schaffner
Journal:  Lancet       Date:  1967-01-28       Impact factor: 79.321

3.  Rosette inhibition test for the demonstration of thymus-dependent lymphocyte sensitization in Grave's disease and Hashimoto's thyroiditis.

Authors:  N R Farid; R E Munro; V V Row; R Volpé
Journal:  N Engl J Med       Date:  1973-11-22       Impact factor: 91.245

4.  Relation between Australia antigen and autoimmune hepatitis.

Authors:  H Popper; I R Mackay
Journal:  Lancet       Date:  1972-05-27       Impact factor: 79.321

5.  Cellular immunity and hepatitis-associated, Australia antigen liver disease.

Authors:  F J Dudley; R A Fox; S Sherlock
Journal:  Lancet       Date:  1972-04-01       Impact factor: 79.321

6.  Lymphopenia and change in distribution of human B and T lymphocytes in peripheral blood induced by irradiation for mammary carcinoma.

Authors:  J Stjernswärd; M Jondal; F Vánky; H Wigzell; R Sealy
Journal:  Lancet       Date:  1972-06-24       Impact factor: 79.321

7.  Tissue antibodies in primary biliary cirrhosis, active chronic (lupoid) hepatitis, cryptogenic cirrhosis and other liver diseases and their clinical implications.

Authors:  D Doniach; I M Roitt; J G Walker; S Sherlock
Journal:  Clin Exp Immunol       Date:  1966-07       Impact factor: 4.330

8.  Clinical evaluation of a rosette inhibition test in renal allotransplantation.

Authors:  A Munro; M Bewick; L Manuel; J S Cameron; F G Ellis; M Boulton-Jones; C S Ogg
Journal:  Br Med J       Date:  1971-07-31

9.  Cell-mediated immunity to a human liver-specific antigen in patients with active chronic hepatitis and primary biliary cirrhosis.

Authors:  J Miller; M G Smith; C G Mitchell; W D Reed; A L Eddleston; R Williams
Journal:  Lancet       Date:  1972-08-12       Impact factor: 79.321

10.  Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.

Authors:  M Jondal; G Holm; H Wigzell
Journal:  J Exp Med       Date:  1972-08-01       Impact factor: 14.307
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  2 in total

Review 1.  Immunologic effector mechanisms in hepatitis B-negative chronic active hepatitis.

Authors:  R J Klingenstein; J R Wands
Journal:  Springer Semin Immunopathol       Date:  1980-12

2.  Alterations of T-cell subsets in primary biliary cirrhosis.

Authors:  A K Bhan; J L Dienstag; J R Wands; S F Schlossman; E L Reinherz
Journal:  Clin Exp Immunol       Date:  1982-02       Impact factor: 4.330
  2 in total

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