Literature DB >> 10863025

Distribution of P2X purinoceptor clusters on individual rat dorsal root ganglion cells.

J A Barden1, M R Bennett.   

Abstract

The distribution of P2X receptors on the cell bodies of acutely dissociated rat dorsal root ganglion cells has been determined using immunohistochemistry. Only medium and small ganglion cells showed P2X receptor labelling, which took the form of receptor clusters 0. 2-0.5 microm in diameter. P2X(3) was the predominant cluster type although clusters of all other subtypes, P2X(1), P2X(2), P2X(4), P2X(5) and P2X(6) were observed. There was little evidence for colocalization of the different receptor subtypes pointing to very little heteropolymerization of P2X receptors in the ganglion.

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Year:  2000        PMID： 10863025     DOI： 10.1016/s0304-3940(00)01150-2

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  7 in total

Review 1.  Molecular and functional properties of P2X receptors--recent progress and persisting challenges.

Authors:  Karina Kaczmarek-Hájek; Eva Lörinczi; Ralf Hausmann; Annette Nicke
Journal:  Purinergic Signal       Date:  2012-05-01       Impact factor: 3.765

2.  Heterogeneity of the functional expression of P2X3 and P2X2/3 receptors in the primary nociceptive neurons of rat.

Authors:  U V Lalo; A N Dashkin; A Krishtal
Journal:  Neurochem Res       Date:  2001-09       Impact factor: 3.996

3.  Localization of P2X7 receptor immunoreactivity in the dorsal root ganglia of guinea pig.

Authors:  Xuegong Bai; Ling Jiang; Zhenghua Xiang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2005

Review 4.  Crossing the pain barrier: P2 receptors as targets for novel analgesics.

Authors:  C Kennedy; T S Assis; A J Currie; E G Rowan
Journal:  J Physiol       Date:  2003-09-26       Impact factor: 5.182

5.  Assessment of the potential role of muscle spindle mechanoreceptor afferents in chronic muscle pain in the rat masseter muscle.

Authors:  James P Lund; Somayeh Sadeghi; Tuija Athanassiadis; Nadia Caram Salas; François Auclair; Benoît Thivierge; Isabel Arsenault; Pierre Rompré; Karl-Gunnar Westberg; Arlette Kolta
Journal:  PLoS One       Date:  2010-06-15       Impact factor: 3.240

6.  Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development.

Authors:  Huai Zhen Ruan; Eamonn Moules; Geoffrey Burnstock
Journal:  Histochem Cell Biol       Date:  2004-11-12       Impact factor: 4.304

7.  The role of purinergic receptors in cancer-induced bone pain.

Authors:  Sarah Falk; Maria Uldall; Anne-Marie Heegaard
Journal:  J Osteoporos       Date:  2012-10-03
  7 in total

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