Literature DB >> 10862195

A clinical pathway to accelerate recovery after colonic resection.

L Basse1, D Hjort Jakobsen, P Billesbølle, M Werner, H Kehlet.   

Abstract

OBJECTIVE: To investigate the feasibility of a 48-hour postoperative stay program after colonic resection. SUMMARY BACKGROUND DATA: Postoperative hospital stay after colonic resection is usually 6 to 12 days, with a complication rate of 10% to 20%. Limiting factors for early recovery include stress-induced organ dysfunction, paralytic ileus, pain, and fatigue. It has been hypothesized that an accelerated multimodal rehabilitation program with optimal pain relief, stress reduction with regional anesthesia, early enteral nutrition, and early mobilization may enhance recovery and reduce the complication rate.
METHODS: Sixty consecutive patients undergoing elective colonic resection were prospectively studied using a well-defined postoperative care program including continuous thoracic epidural analgesia and enforced early mobilization and enteral nutrition, and a planned 48-hour postoperative hospital stay. Postoperative follow-up was scheduled at 8 and 30 days.
RESULTS: Median age was 74 years, with 20 patients in ASA group III-IV. Normal gastrointestinal function (defecation) occurred within 48 hours in 57 patients, and the median hospital stay was 2 days, with 32 patients staying 2 days after surgery. There were no cardiopulmonary complications. The readmission rate was 15%, including two patients with anastomotic dehiscence (one treated conservatively, one with colostomy); other readmissions required only short-term observation.
CONCLUSION: A multimodal rehabilitation program may significantly reduce the postoperative hospital stay in high-risk patients undergoing colonic resection. Such a program may also reduce postoperative ileus and cardiopulmonary complications. These results may have important implications for the care of patients after colonic surgery and in the future assessment of open versus laparoscopic colonic resection.

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Year:  2000        PMID: 10862195      PMCID: PMC1421107          DOI: 10.1097/00000658-200007000-00008

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  19 in total

1.  "Ideal" length of stay after colectomy: whose ideal?

Authors:  D J Schoetz; M Bockler; M S Rosenblatt; S Malhotra; P L Roberts; J J Murray; J A Coller; L C Rusin
Journal:  Dis Colon Rectum       Date:  1997-07       Impact factor: 4.585

2.  Colorectal surgery in octogenarians.

Authors:  H Spivak; D V Maele; I Friedman; M Nussbaum
Journal:  J Am Coll Surg       Date:  1996-07       Impact factor: 6.113

Review 3.  Multimodal approach to control postoperative pathophysiology and rehabilitation.

Authors:  H Kehlet
Journal:  Br J Anaesth       Date:  1997-05       Impact factor: 9.166

4.  Perioperative management of colon cancer under Medicare risk programs.

Authors:  S M Retchin; L Penberthy; C Desch; R Brown; B Jerome-D'Emilia; D Clement
Journal:  Arch Intern Med       Date:  1997-09-08

Review 5.  Acute pain control and accelerated postoperative surgical recovery.

Authors:  H Kehlet
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6.  Recovery after laparoscopic colonic surgery with epidural analgesia, and early oral nutrition and mobilisation.

Authors:  L Bardram; P Funch-Jensen; P Jensen; M E Crawford; H Kehlet
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7.  Hospital costs and severity of illness in three types of elective surgery.

Authors:  A Macario; T S Vitez; B Dunn; T McDonald; B Brown
Journal:  Anesthesiology       Date:  1997-01       Impact factor: 7.892

8.  Convalescence and hospital stay after colonic surgery with balanced analgesia, early oral feeding, and enforced mobilisation.

Authors:  S Møiniche; S Bülow; P Hesselfeldt; A Hestbaek; H Kehlet
Journal:  Eur J Surg       Date:  1995-04

9.  Morbidity and mortality following laparoscopic-assisted right hemicolectomy for cancer.

Authors:  E L Bokey; J W Moore; P H Chapuis; R C Newland
Journal:  Dis Colon Rectum       Date:  1996-10       Impact factor: 4.585

10.  Effects of perioperative analgesic technique on rate of recovery after colon surgery.

Authors:  S S Liu; R L Carpenter; D C Mackey; R C Thirlby; S M Rupp; T S Shine; N G Feinglass; P P Metzger; J T Fulmer; S L Smith
Journal:  Anesthesiology       Date:  1995-10       Impact factor: 7.892

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  178 in total

Review 1.  Management of patients in fast track surgery.

Authors:  D W Wilmore; H Kehlet
Journal:  BMJ       Date:  2001-02-24

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Authors:  Kathrine Holte; Henrik Kehlet
Journal:  Drugs       Date:  2002       Impact factor: 9.546

3.  Enhanced recovery program following colorectal resection in the elderly patient.

Authors:  Nikhil Pawa; Paul L Cathcart; Tan H A Arulampalam; Matthew G Tutton; Roger W Motson
Journal:  World J Surg       Date:  2012-02       Impact factor: 3.352

4.  Feasibility of enhanced recovery programme in various patient groups.

Authors:  Paul M Verheijen; Anthony W H Vd Ven; Paul H P Davids; Bryan J M Vd Wall; Apollo Pronk
Journal:  Int J Colorectal Dis       Date:  2011-11-12       Impact factor: 2.571

5.  Influence of major surgery on the mannan-binding lectin pathway of innate immunity.

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9.  ["Fast-track" colonic surgery-first experience with a clinical procedure for accelerating postoperative recovery].

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Review 10.  Fast-track programmes for hepatopancreatic resections: where do we stand?

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