Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Ultrastructural study of Reed-Sternberg cells. Comparison with transformed lymphocytes and histiocytes.

Literature DB >> 1086064

Ultrastructural study of Reed-Sternberg cells. Comparison with transformed lymphocytes and histiocytes.

A D Glick, J H Leech, J M Flexner, R D Collins.

Abstract

The ultrastructural features of Reed-Sternberg cells from 17 patients with Hodgkin's disease were compared with those of histiocytes and transformed lymphocytes in both benign and malignant conditions. Transformed lymphocytes and Reed-Sternberg cells appeared to have similar features, including large nuclei with dispersed chromatin, large nucleoli, and great numbers of cytoplasmic polyribosomes. Histiocytes contained abundant cytoplasmic lysosomal granules and microfilaments. These results are indicative of the origin of Reed-Sternberg cells from lymphocytes.

Entities: Disease Species

Mesh：

Year: 1976 PMID： 1086064 PMCID： PMC2032544

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

12 in total

1. Cytology of the Sternberg-Reed cell as revealed by the electron microscope.

Authors: W J FRAJOLA; M H GREIDER; B A BOURONCLE
Journal: Ann N Y Acad Sci Date: 1958-09-05 Impact factor: 5.691

2. Electron Microscopic investigations on sections from lymph nodes and bone marrow in malignant blood diseases.

Authors: H BRAUNSTEINER; K FELLINGER; F PAKESCH
Journal: Blood Date: 1957-03 Impact factor: 22.113

3. Immunoglobulin-positive Reed Sternberg cells in Hodgkin's disease.

Authors: J Leech
Journal: Lancet Date: 1973-08-04 Impact factor: 79.321

4. The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells.

Authors: R van Furth; Z A Cohn; J G Hirsch; J H Humphrey; W G Spector; H L Langevoort
Journal: Bull World Health Organ Date: 1972 Impact factor: 9.408

5. Identification of promonocytes and monocytoid precursors in acute leukaemia of adults: ultrastructural and cytochemical observations.

Authors: A D Glick; R G Horn
Journal: Br J Haematol Date: 1974-03 Impact factor: 6.998

6. Ultrastructural studies of Hodgkin's disease.

Authors: R F Dorfman; D F Rice; A D Mitchell; R L Kempson; G Levine
Journal: Natl Cancer Inst Monogr Date: 1973-05

7. Proliferation characteristics of the various classes of cells in Hodgkin's disease.

Authors: M J Peckham; E H Cooper
Journal: Cancer Date: 1969-07 Impact factor: 6.860

Review 8. Human lymphocyte growth in vitro: morphologic, biochemical, and immunologic significance.

Authors: S D Douglas
Journal: Int Rev Exp Pathol Date: 1971

9. Malignant lymphomas of follicular center cell origin in man. II. Ultrastructural and cytochemical studies.

Authors: A D Glick; J H Leech; J A Waldron; J M Flexner; R G Horn; R D Collins
Journal: J Natl Cancer Inst Date: 1975-01 Impact factor: 13.506

10. Immunohistochemical demonstration of IgG in Reed-Sternberg and other cells in Hodgkin's disease.

Authors: A J Garvin; S S Spicer; R T Parmley; A M Munster
Journal: J Exp Med Date: 1974-05-01 Impact factor: 14.307

17 in total

1. Establishment of a malignant, Epstein-Barr-virus (EBV)-negative cell-line from the pleura effusion of a patient with Hodgkin's disease.

Authors: M Schaadt; C Fonatsch; H Kirchner; V Diehl
Journal: Blut Date: 1979-02-19

2. Immunopathology of Hodgkin's disease. Characterization of Reed-Sternberg cells with monoclonal antibodies.

Authors: J A Strauchen; A Dimitriu-Bona
Journal: Am J Pathol Date: 1986-05 Impact factor: 4.307

Review 3. Malignant lymphomas--a conceptual understanding of morphologic diversity. A review.

Authors: R B Mann; E S Jaffe; C W Berard
Journal: Am J Pathol Date: 1979-01 Impact factor: 4.307

4. Pathophysiological aspects of Hodgkin's disease.

Authors: D Huhn
Journal: Klin Wochenschr Date: 1979-05-16

5. Leu-M1--a marker for Reed-Sternberg cells in Hodgkin's disease. An immunoperoxidase study of paraffin-embedded tissues.

Authors: G S Pinkus; P Thomas; J W Said
Journal: Am J Pathol Date: 1985-05 Impact factor: 4.307

6. Immunohistological analysis of Hodgkin's and Sternberg-reed cells: detection of a new antigen and evidence for selective IgG uptake in the absence of B cell, T cell and histiocytic markers.

Authors: H Stein; J Gerdes; H Kirchner; V Diehl; M Schaadt; A Bonk; T Steffen
Journal: J Cancer Res Clin Oncol Date: 1981 Impact factor: 4.553