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Literature DB >> 10860393

Hypervitaminosis A and bone.

Abstract

Animal, human, and in vitro data all indicate that excess vitamin A stimulates bone resorption and inhibits bone formation. This combination would be expected to produce bone loss and to contribute to osteoporosis development and may occur with relatively low vitamin A intake. It is possible that unappreciated hypervitaminosis A contributes to osteoporosis pathogenesis.

Entities: Chemical Disease Species

Mesh：

Substances：
Retinoids

Year: 2000 PMID： 10860393 DOI： 10.1111/j.1753-4887.2000.tb01848.x

Source DB: PubMed Journal: Nutr Rev ISSN： 0029-6643 Impact factor: 7.110

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Cited

22 in total

1. Cod liver oil consumption at different periods of life and bone mineral density in old age.

Authors: Tinna Eysteinsdottir; Thorhallur I Halldorsson; Inga Thorsdottir; Gunnar Sigurdsson; Sigurdur Sigurdsson; Tamara Harris; Lenore J Launer; Vilmundur Gudnason; Ingibjorg Gunnarsdottir; Laufey Steingrimsdottir
Journal: Br J Nutr Date: 2015-06-16 Impact factor: 3.718

2. Restricting vitamin A intake increases bone formation in Zambian children with high liver stores of vitamin.

Authors: S A Tanumihardjo; B M Gannon; C Kaliwile; J Chileshe; N C Binkley
Journal: Arch Osteoporos Date: 2019-06-28 Impact factor: 2.617

3. Retinol-binding protein 4 is expressed in chondrocytes of developing mouse long bones: implications for a local role in formation of the secondary ossification center.

Authors: Jodie T Hatfield; Peter J Anderson; Barry C Powell
Journal: Histochem Cell Biol Date: 2012-12-06 Impact factor: 4.304

4. Vitamins and sleep: an exploratory study.

Authors: Kenneth L Lichstein; Kristen L Payne; James P Soeffing; H Heith Durrence; Daniel J Taylor; Brant W Riedel; Andrew J Bush
Journal: Sleep Med Date: 2007-09-06 Impact factor: 3.492

5. Vitamin A and retinol intakes and the risk of fractures among participants of the Women's Health Initiative Observational Study.

Authors: Graciela Caire-Juvera; Cheryl Ritenbaugh; Jean Wactawski-Wende; Linda G Snetselaar; Zhao Chen
Journal: Am J Clin Nutr Date: 2008-12-03 Impact factor: 7.045

Hypervitaminosis A and bone.

1. Cod liver oil consumption at different periods of life and bone mineral density in old age.

2. Restricting vitamin A intake increases bone formation in Zambian children with high liver stores of vitamin.

3. Retinol-binding protein 4 is expressed in chondrocytes of developing mouse long bones: implications for a local role in formation of the secondary ossification center.

4. Vitamins and sleep: an exploratory study.

5. Vitamin A and retinol intakes and the risk of fractures among participants of the Women's Health Initiative Observational Study.

6. Vitamin A intake and the risk of hip fracture in postmenopausal women: the Iowa Women's Health Study.

7. No dose-dependent increase in fracture risk after long-term exposure to high doses of retinol or beta-carotene.

8. No effect of vitamin A intake on bone mineral density and fracture risk in perimenopausal women.

9. Case of hypercalcemia secondary to hypervitaminosis a in a 6-year-old boy with autism.

10. Vitamin a is a negative regulator of osteoblast mineralization.