Literature DB >> 10859563

Mass spectrometry for genotyping: an emerging tool for molecular medicine.

P E Jackson1, P F Scholl, J D Groopman.   

Abstract

Recent technological innovations have made proteins and nucleic acids accessible to mass spectrometric analysis. As a result of their inherently high specificity, accuracy and throughput, there is considerable interest in developing mass spectrometric methods for genotype analysis in clinical diagnostic and research applications. This review outlines some of the most promising genotyping methods developed using electrospray and matrix-assisted laser-desorption-ionization mass spectrometry.

Mesh:

Year:  2000        PMID: 10859563     DOI: 10.1016/s1357-4310(00)01698-1

Source DB:  PubMed          Journal:  Mol Med Today        ISSN: 1357-4310


  6 in total

Review 1.  Science, medicine, and the future: Postgenomic technologies: hunting the genes for common disorders.

Authors:  C Mathew
Journal:  BMJ       Date:  2001-04-28

2.  The association of DNA sequence variation at the MAOA genetic locus with quantitative behavioural traits in normal males.

Authors:  Shai Rosenberg; Alan R Templeton; Paul D Feigin; Doron Lancet; Jacques S Beckmann; Sara Selig; Dean H Hamer; Karl Skorecki
Journal:  Hum Genet       Date:  2006-08-02       Impact factor: 4.132

3.  Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer.

Authors:  Erin E Bessette; Angela K Goodenough; Sophie Langouët; Isil Yasa; Ivan D Kozekov; Simon D Spivack; Robert J Turesky
Journal:  Anal Chem       Date:  2009-01-15       Impact factor: 6.986

4.  Ferrocene conjugates of dUTP for enzymatic redox labelling of DNA.

Authors:  Wjatschesslaw A Wlassoff; Garry C King
Journal:  Nucleic Acids Res       Date:  2002-06-15       Impact factor: 16.971

5.  Nosocomial malaria and saline flush.

Authors:  Sanjay K Jain; Deborah Persaud; Trish M Perl; Margaret A Pass; Kathleen M Murphy; John M Pisciotta; Peter F Scholl; James F Casella; David J Sullivan
Journal:  Emerg Infect Dis       Date:  2005-07       Impact factor: 6.883

6.  Cysteine-Rich Peptide Fingerprinting as a General Method for Herbal Analysis to Differentiate Radix Astragali and Radix Hedysarum.

Authors:  Jiayi Huang; Ka H Wong; Stephanie V Tay; Adrian How; James P Tam
Journal:  Front Plant Sci       Date:  2019-07-31       Impact factor: 5.753

  6 in total

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