Literature DB >> 10859562

The role of nonhuman primate models in AIDS vaccine development.

M I Johnston1.   

Abstract

Although animal models have been useful in guiding vaccine development, HIV/AIDS models have not yielded a clear correlate of immunity nor given consistent results on the potential efficacy of various vaccine approaches. Further development and improved uniformity in the use of animal models would maximize their potential to meet the urgent worldwide need for a safe and effective HIV vaccine.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10859562     DOI： 10.1016/s1357-4310(00)01724-x

Source DB:  PubMed          Journal:  Mol Med Today        ISSN： 1357-4310


  7 in total

1.  Induction of mucosal protection against primary, heterologous simian immunodeficiency virus by a DNA vaccine.

Authors:  Deborah Heydenburg Fuller; Premeela A Rajakumar; Lawrence A Wilson; Anita M Trichel; James T Fuller; Tim Shipley; Mary S Wu; Kathleen Weis; Charles R Rinaldo; Joel R Haynes; Michael Murphey-Corb
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

2.  Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design?

Authors:  V Novitsky; U R Smith; P Gilbert; M F McLane; P Chigwedere; C Williamson; T Ndung'u; I Klein; S Y Chang; T Peter; I Thior; B T Foley; S Gaolekwe; N Rybak; S Gaseitsiwe; F Vannberg; R Marlink; T H Lee; M Essex
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

3.  Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge.

Authors:  Santhi Gorantla; Kathlyn Santos; Vakara Meyer; Stephen Dewhurst; William J Bowers; Howard J Federoff; Howard E Gendelman; Larisa Poluektova
Journal:  J Virol       Date:  2005-02       Impact factor: 5.103

4.  Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C.

Authors:  V Novitsky; H Cao; N Rybak; P Gilbert; M F McLane; S Gaolekwe; T Peter; I Thior; T Ndung'u; R Marlink; T H Lee; M Essex
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

5.  The institutional review board is an impediment to human research: the result is more animal-based research.

Authors:  Mark J Rice
Journal:  Philos Ethics Humanit Med       Date:  2011-06-07       Impact factor: 2.464

6.  Protection against SHIV-KB9 infection by combining rDNA and rFPV vaccines based on HIV multiepitope and p24 protein in Chinese rhesus macaques.

Authors:  Chang Li; Zhenwei Shen; Xiao Li; Jieying Bai; Lin Zeng; Mingyao Tian; Ying Jin Song; Ming Ye; Shouwen Du; Dayong Ren; Cunxia Liu; Na Zhu; Dandan Sun; Yi Li; Ningyi Jin
Journal:  Clin Dev Immunol       Date:  2012-02-26

7.  A review of the Institute of Medicine's analysis of using chimpanzees in biomedical research.

Authors:  Robert C Jones; Ray Greek
Journal:  Sci Eng Ethics       Date:  2013-04-25       Impact factor: 3.525
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.