Literature DB >> 10859419

Oxidative modification of low-density lipoprotein (LDL) in HD patients: role in electronegative LDL formation.

O Ziouzenkova1, A Sevanian.   

Abstract

High cardiovascular mortality in patients on hemodialysis (HD) is largely attributed to oxidative stress and altered lipoprotein profiles. Markedly increased levels of mildly modified LDL subfractions, such as dense LDL and electronegatively charged LDL (LDL(-)), are present in the blood of HD patients and may be markers of atherosclerosis risk. LDL(-), characterized by modified protein content and elevated levels of lipid peroxidation products, is representative of multiple oxidative processes acting on plasma lipoproteins that prevail during HD. In this review, we discussed known mechanisms leading to that may account for oxidative protein modification and/or LDL(-) formation in the context of specific conditions associated with HD. Copyright 2000 S. Karger AG, Basel

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Year:  2000        PMID： 10859419     DOI： 10.1159/000014415

Source DB:  PubMed          Journal:  Blood Purif        ISSN： 0253-5068            Impact factor:   2.614


  7 in total

1.  Aggregated electronegative low density lipoprotein in human plasma shows a high tendency toward phospholipolysis and particle fusion.

Authors:  Cristina Bancells; Sandra Villegas; Francisco J Blanco; Sonia Benítez; Isaac Gállego; Lorea Beloki; Montserrat Pérez-Cuellar; Jordi Ordóñez-Llanos; José Luis Sánchez-Quesada
Journal:  J Biol Chem       Date:  2010-07-29       Impact factor: 5.157

2.  Soy isoflavones reduce electronegative low-density lipoprotein (LDL(-)) and anti-LDL (-) autoantibodies in experimental atherosclerosis.

Authors:  Nágila Raquel Teixeira Damasceno; Elaine Apolinário; Fabiana Dias Flauzino; Irene Fernandes; Dulcineia Saes Parra Abdalla
Journal:  Eur J Nutr       Date:  2007-01-30       Impact factor: 5.614

3.  Dual roles for lipolysis and oxidation in peroxisome proliferation-activator receptor responses to electronegative low density lipoprotein.

Authors:  Ouliana Ziouzenkova; Liana Asatryan; Deanna Sahady; Gabriela Orasanu; Stephan Perrey; Benjamin Cutak; Tom Hassell; Taro E Akiyama; Joel P Berger; Alex Sevanian; Jorge Plutzky
Journal:  J Biol Chem       Date:  2003-07-23       Impact factor: 5.157

4.  Lipid Peroxidation, Advanced Glycation end Products and Antioxidant Status in Patients on Dialysis.

Authors:  Anna Stefanska; Grazyna Sypniewska; Rafal Donderski; Jacek Manitius
Journal:  EJIFCC       Date:  2005-03-04

5.  One-Year Conservative Care Using Sodium Bicarbonate Supplementation Is Associated with a Decrease in Electronegative LDL in Chronic Kidney Disease Patients: A Pilot Study.

Authors:  Felipe Rizzetto; Denise Mafra; Ana Beatriz Barra; Gisella Pires de Melo; Dulcinéia Saes Parra Abdalla; Maurilo Leite
Journal:  Cardiorenal Med       Date:  2017-08-17       Impact factor: 2.041

6.  Paricalcitol reduces oxidative stress and inflammation in hemodialysis patients.

Authors:  María Jesús Izquierdo; Mónica Cavia; Pilar Muñiz; Angel L M de Francisco; Manuel Arias; Javier Santos; Pedro Abaigar
Journal:  BMC Nephrol       Date:  2012-11-27       Impact factor: 2.388

7.  Redox State of Human Serum Albumin and Inflammatory Biomarkers in Hemodialysis Patients with Secondary Hyperparathyroidism During Oral Calcitriol Supplementation for Vitamin D.

Authors:  Wesam A Nasif; Mohammed H Mukhtar; Hoda M El-Emshaty; Ahmed H Alwazna
Journal:  Open Med Chem J       Date:  2018-10-18
  7 in total

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