Literature DB >> 1085703

Fc-rosetting and nonrosetting T cells are killer cells.

P H Krammer, B E Elliott, H von Boehmer.   

Abstract

A fraction of T cells activated to H-2 determinants in vivo (ATO) express Fc receptors (FcR) on the cell surface. Those FcR can be detected by antibody coated red blood cells (EA rosettes). Nonrosetting and EA rosetting ATC could be obtained in highly enriched form (more than 99% pure) by separation by velocity sedimentation at unit gravity. Separately tested, both fractions of ATC showed killer cell activity against specific target cells. Possible explanations why only one population of T killer cells expressed FcR are discussed.

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Year:  1976        PMID: 1085703     DOI: 10.1002/eji.1830060214

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN: 0014-2980            Impact factor:   5.532


  2 in total

1.  Contribution of lymphocytes bearing Fcgamma receptors to PHA-induced cytotoxicity.

Authors:  G Cordier; C Samarut; J P Revillard
Journal:  Immunology       Date:  1978-07       Impact factor: 7.397

2.  Immunological properties of Fc receptor on lymphocytes. VIII. The behaviour of FcR+ and FcR- T cells in cell-mediated immune responses.

Authors:  A Takabayashi; T Masuda; S Suzuki; M Hanaoka
Journal:  Immunology       Date:  1980-02       Impact factor: 7.397

  2 in total

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