Literature DB >> 1085609

Neonatal pyridoxine responsive convulsions due to isoniazid therapy.

S A McKenzie, A J Macnab, G Katz.   

Abstract

A 17-day-old infant on isoniazid therapy 13 mg/kg daily from birth because of maternal tuberculosis was admitted after 4 days of clonic fits. No underlying infective or biochemical cause could be found. The fits ceased within 4 hours of administering intramuscular pyridoxine, suggesting an aetiology of pyridoxine deficiency secondary to isoniazid medication.

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Year:  1976        PMID: 1085609      PMCID: PMC1546048          DOI: 10.1136/adc.51.7.567

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  7 in total

1.  The effect of isoniazid therapy on pyridoxine metabolism in children.

Authors:  S M MORALES; E M LINCOLN
Journal:  Am Rev Tuberc       Date:  1957-04

2.  Effects of isoniazid on pyridoxine metabolism.

Authors:  J P BIEHL; R W VILTER
Journal:  J Am Med Assoc       Date:  1954-12-25

3.  Convulsive seizures in infants with pyridoxine-deficient diet.

Authors:  D B COURSIN
Journal:  J Am Med Assoc       Date:  1954-01-30

4.  Sequelae of neonatal convulsions. Study of 112 infants.

Authors:  J H Keen; D Lee
Journal:  Arch Dis Child       Date:  1973-07       Impact factor: 3.791

5.  Pyridoxine dependency convulsions in a newborn.

Authors:  M M Robins
Journal:  JAMA       Date:  1966-02-07       Impact factor: 56.272

6.  Pyridoxine deficiency in the human infant.

Authors:  S E SNYDERMAN; L E HOLT; R CARRETERO; K JACOBS
Journal:  J Clin Nutr       Date:  1953 Mar-Apr

7.  Pyridoxine dependency: report of a case of intractable convulsions in an infant controlled by pyridoxine.

Authors:  A D HUNT; J STOKES; W W McCRORY; H H STROUD
Journal:  Pediatrics       Date:  1954-02       Impact factor: 7.124

  7 in total
  2 in total

Review 1.  Drugs and vitamin deficiency.

Authors:  L Ovesen
Journal:  Drugs       Date:  1979-10       Impact factor: 9.546

Review 2.  Neurological manifestations and toxicities of the antituberculosis drugs. A review.

Authors:  M R Holdiness
Journal:  Med Toxicol       Date:  1987 Jan-Feb
  2 in total

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