Literature DB >> 10853421

[The MDR gene and cellular sensitivity to various effects].

S G Zubova1, A O Danilov, A I Myshkov, T V Bykova, A Iu Zaritskiĭ, V B Okulov.   

Abstract

mdr-Transfected K-562 cells revealed a relatively high resistance to cytotoxic monokines and ionizing radiation as compared to parental cells. Taken together with what is known about the resistance of mdr-expressing cells to multiple cytotoxic drugs, our results point to malignant cells having universal mechanisms of chemo-, bio- and radioresistance.

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Year:  2000        PMID: 10853421

Source DB:  PubMed          Journal:  Vopr Onkol        ISSN: 0507-3758


  1 in total

1.  Autophagy inhibition plays the synergetic killing roles with radiation in the multi-drug resistant SKVCR ovarian cancer cells.

Authors:  Bing Liang; Dejuan Kong; Yang Liu; Nan Liang; Mengzi He; Shumei Ma; Xiaodong Liu
Journal:  Radiat Oncol       Date:  2012-12-17       Impact factor: 3.481

  1 in total

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