Literature DB >> 1085235

Hidden' IgG antiglobulins in normal human serum.

F C Hay, L J Nineham, G Torrigiani, I M Roitt.   

Abstract

Hidden antiglobulins reacting with whole rabbit immunoglobulin were found by radioassay or indirect haemagglutination after gel filtration or ultracentrifugation of normal serum. Suprisingly, both the IgM and IgG antiglobulins were present in the same macroglobulin fractions. The IgG antiglobulins could be dissociated into 7S components by separating the serum under acid conditions. Antiglobulin activity was a function of the Fab region.

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Year:  1976        PMID： 1085235      PMCID： PMC1541363     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  11 in total

1.  Anti-gamma-globulin factors in human sera revealed by enzymatic splitting of anti-Rh antibodies.

Authors:  C K OSTERLAND; M HARBOE; H G KUNKEL
Journal:  Vox Sang       Date:  1963 Mar-Apr       Impact factor: 2.144

2.  Gamma globulin complexes in rheumatoid arthritis and certain other conditions.

Authors:  H G KUNKEL; H J MULLER-EBERHARD; H H FUDENBERG; T B TOMASI
Journal:  J Clin Invest       Date:  1961-01       Impact factor: 14.808

3.  Preparation of iodine-131 labelled human growth hormone of high specific activity.

Authors:  W M HUNTER; F C GREENWOOD
Journal:  Nature       Date:  1962-05-05       Impact factor: 49.962

4.  Presence of aggregated gamma-G-globulin in certain rheumatoid synovial effusions.

Authors:  K Hannestad
Journal:  Clin Exp Immunol       Date:  1967-07       Impact factor: 4.330

5.  Hidden rheumatoid factors with specificity for native gamma globulins.

Authors:  J C Allen; H G Kunkel
Journal:  Arthritis Rheum       Date:  1966-12

6.  Antiglobulin factors in sera from patients with rheumatoid arthritis and normal subjects. Quantitative estimation in different immunoglobulin classes.

Authors:  G Torrigiani; I M Roitt
Journal:  Ann Rheum Dis       Date:  1967-07       Impact factor: 19.103

7.  Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors:  G Mancini; A O Carbonara; J F Heremans
Journal:  Immunochemistry       Date:  1965-09

8.  Raised IgG antiglobulin factors in Still's disease.

Authors:  G Torrigiani; B M Ansell; E E Chown; I M Roitt
Journal:  Ann Rheum Dis       Date:  1969-07       Impact factor: 19.103

9.  The molecular basis of self-association of antibodies to IgG (rheumatoid factors) in rheumatoid arthritis.

Authors:  R M Pope; D C Teller; M Mannik
Journal:  Proc Natl Acad Sci U S A       Date:  1974-02       Impact factor: 11.205

10.  THE ENHANCEMENT OF 19S ANTIBODY PRODUCTION BY PARTICULATE ANTIGEN.

Authors:  G TORRIGIANI; I M ROITT
Journal:  J Exp Med       Date:  1965-07-01       Impact factor: 14.307
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  7 in total

1.  Immune complexes in cord serum: influence of sex, gestational age, and Rh- blood group--possible predictive value of high levels for early postnatal infections.

Authors:  C M Farber; C L Cambiaso; P L Masson
Journal:  Clin Exp Immunol       Date:  1981-05       Impact factor: 4.330

2.  Complexed rheumatoid factor measurements in sera, synovial fluids and in immune complex fractions.

Authors:  A Falus; K Merétey; U Böhm; S Bozsóky
Journal:  Experientia       Date:  1979-03-15

3.  M cell-targeted ocular immunization: effect on immunoglobulins in tears, feces, and serum.

Authors:  Thomas E Phillips; Jeremy Sharp; Kay Rodgers; Hongshan Liu
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-11-05       Impact factor: 4.799

4.  Immune complexes in serum and in cerebrospinal fluid in African trypanosomiasis. Correlation with polyclonal B cell activation and with intracerebral immunoglobulin synthesis.

Authors:  P H Lambert; M Berney; G Kazyumba
Journal:  J Clin Invest       Date:  1981-01       Impact factor: 14.808

5.  The elution of IgG from subacute sclerosing panencephalitis and multiple sclerosis brains.

Authors:  C J Sindic; C L Cambiaso; P L Masson; E C Laterre
Journal:  Clin Exp Immunol       Date:  1980-07       Impact factor: 4.330

6.  The binding constants of IgM rheumatoid factors and their univalent fragments for native and aggregated human IgG;.

Authors:  S Dissanayake; F C Hay; I M Roitt
Journal:  Immunology       Date:  1977-03       Impact factor: 7.397

7.  False positivity of non-targeted infections in malaria rapid diagnostic tests: the case of human african trypanosomiasis.

Authors:  Philippe Gillet; Dieudonné Mumba Ngoyi; Albert Lukuka; Viktor Kande; Benjamin Atua; Johan van Griensven; Jean-Jacques Muyembe; Jan Jacobs; Veerle Lejon
Journal:  PLoS Negl Trop Dis       Date:  2013-04-25
  7 in total

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