A hypothesis on the biochemistry of spontaneous remissions of cancer: coupling of oxidative phosphorylation and the remission of cancer.

Aggressively growing tumors are highly dependent on the blood glucose supply. Whenever the blood glucose supply is high they grow rapidly and whenever the blood glucose supply is low they grow slowly. In cases of bonafide reports of spontaneous remissions and regressions of cancer, this tumor regulatory mechanism fails and the tumor grows rapidly and steadily despite a low blood glucose supply. This results in the collapse of the tumor system and its removal by the immune system. In lay language, it can be compared to a car that can be driven safely at 60 mph, but if it is driven at 200 mph, it will turn over and stop. Accelerated tumor growth can be induced in many ways such as: (a) reducing tumor mass which will result in a compensatory tumor growth; (b) administering hormones; (c) increasing body temperature; (d) reducing blood cortisol level; and (e) temporarily suppressing cellular immunity. A simple example would be a case of a patient with advanced and widespread cancer. If the tumor mass is reduced at once it will result in compensatory tumor growth and if hypoglycemia is initiated just prior to reducing the tumor mass and the hypoglycemia is maintained, it could possibly be followed with a brief tumor growth and the remission of cancer. The suggested procedure has not been tested or proven to be correct as yet; it is not recommended unless done under careful supervision.