Literature DB >> 10849679

The metabolic hypothesis revisited.

C Rozanov1, A Roy, A Mokashi, S Osanai, P Daudu, B Storey, S Lahiri.   

Abstract

High levels of CO are used to mimic the stimulatory response of the CSN initiated by hypoxia. Using light of different wavelengths we show that the stimulatory effects of high CO can be pinpointed to the cytochrome c oxidase in the mitochondrial respiratory chain. This supports the metabolic theory of oxygen sensing in the mitochondria.

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Year:  2000        PMID: 10849679     DOI: 10.1007/0-306-46825-5_37

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  1 in total

1.  Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas.

Authors:  Ying-Jie Peng; Jeffrey L Overholt; David Kline; Ganesh K Kumar; Nanduri R Prabhakar
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-07       Impact factor: 11.205

  1 in total

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