Literature DB >> 10848498

Inflated false-positive rates in Hardy-Weinberg and linkage-equilibrium tests are due to sampling on the basis of rare familial phenotypes in finite populations.

J D Terwilliger.   

Abstract

Mesh:

Year:  2000        PMID: 10848498      PMCID: PMC1287089          DOI: 10.1086/302964

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN: 0002-9297            Impact factor:   11.025


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  11 in total

1.  Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified.

Authors:  H H Göring; J D Terwilliger
Journal:  Am J Hum Genet       Date:  2000-03-23       Impact factor: 11.025

2.  QTL fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium at a series of linked marker loci in extreme samples of populations.

Authors:  H W Deng; W M Chen; R R Recker
Journal:  Am J Hum Genet       Date:  2000-03       Impact factor: 11.025

3.  Linkage strategies for genetically complex traits. I. Multilocus models.

Authors:  N Risch
Journal:  Am J Hum Genet       Date:  1990-02       Impact factor: 11.025

Review 4.  Linkage disequilibrium mapping of complex disease: fantasy or reality?

Authors:  J D Terwilliger; K M Weiss
Journal:  Curr Opin Biotechnol       Date:  1998-12       Impact factor: 9.740

5.  Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus.

Authors:  D M Nielsen; M G Ehm; B S Weir
Journal:  Am J Hum Genet       Date:  1998-11       Impact factor: 11.025

6.  True and false positive peaks in genomewide scans: applications of length-biased sampling to linkage mapping.

Authors:  J D Terwilliger; W D Shannon; G M Lathrop; J P Nolan; L R Goldin; G A Chase; D E Weeks
Journal:  Am J Hum Genet       Date:  1997-08       Impact factor: 11.025

7.  Genetic linkage, gene-locus assignment, and the association of alleles with diseases.

Authors:  G A Chase
Journal:  Transplant Proc       Date:  1977-03       Impact factor: 1.066

8.  Problems in the assessment of relative risk of chronic disease among biological relatives of affected individuals.

Authors:  K M Weiss; R Chakraborty; P P Majumder; P E Smouse
Journal:  J Chronic Dis       Date:  1982

Review 9.  Gene mapping in the 20th and 21st centuries: statistical methods, data analysis, and experimental design.

Authors:  J D Terwilliger; H H Göring
Journal:  Hum Biol       Date:  2000-02       Impact factor: 0.553

10.  A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci.

Authors:  I Hovatta; T Varilo; J Suvisaari; J D Terwilliger; V Ollikainen; R Arajärvi; H Juvonen; M L Kokko-Sahin; L Väisänen; H Mannila; J Lönnqvist; L Peltonen
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

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  5 in total

1.  QTL fine mapping, in extreme samples of finite populations, for complex traits with familial correlation due to polygenes.

Authors:  H W Deng; W M Chen
Journal:  Am J Hum Genet       Date:  2000-07       Impact factor: 11.025

Review 2.  Complex and segmental uniparental disomy (UPD): review and lessons from rare chromosomal complements.

Authors:  D Kotzot
Journal:  J Med Genet       Date:  2001-08       Impact factor: 6.318

3.  Genome-wide autozygosity mapping in human populations.

Authors:  Shuang Wang; Chad Haynes; Francis Barany; Jurg Ott
Journal:  Genet Epidemiol       Date:  2009-02       Impact factor: 2.135

4.  Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study.

Authors:  Richard Sherva; Orapan Sripichai; Kenneth Abel; Qianli Ma; Johanna Whitacre; Vach Angkachatchai; Wattanan Makarasara; Pranee Winichagoon; Saovaros Svasti; Suthat Fucharoen; Andreas Braun; Lindsay A Farrer
Journal:  BMC Med Genet       Date:  2010-03-30       Impact factor: 2.103

5.  Effect of FTO Gene and Physical Activity Interaction on Trunk Fat Percentage Among the Newfoundland Population.

Authors:  Anthony Payne; Farrell Cahill; Guang Sun; J Concepción Loredo-Osti; Taraneh Abarin
Journal:  Genet Epigenet       Date:  2014-06-11
  5 in total

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