Literature DB >> 1084708

Indentification and radioimmunologic estimation of sexual steroid hormones in aqueous humor and vitreous of rabbit eye.

L Stárka, R Hampl, M Bicíková, J Obenberger.   

Abstract

The occurrence of testosterone, estrone, and estradiol-17 alpha in aqueous humor and vitreous body of the rabbit eye was demonstrated. The identity of the steroid hormones was confirmed by their chromatographic properties, microreactions, and radiochemically by crystallization to constant specific activity of their labeled acetates. The levels of testosterone and estrogens in rabbit male and female plasma, aqueous, and vitreous were determined by radioimmunologic assay. The concentrations of the steroid hormones in plasma are higher than in aqueous and vitreous. However, testosterone in aqueous circulates in free form and lacks the binding to sexual hormone-binding globulin as in plasma.

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Year:  1976        PMID： 1084708     DOI： 10.1007/bf00417296

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN： 0065-6100


  12 in total

1.  [Favorable results of anabolic therapy in cases of retinal degeneration].

Authors:  H Sobieska-Clarowa
Journal:  Klin Oczna       Date:  1975-07

2.  [Metabolism of estrone, estradiol-17 alpha and estradiol-17 beta in rabbit liver].

Authors:  H BREUER; G PANGELS
Journal:  Acta Endocrinol (Copenh)       Date:  1960-04

3.  [Local administration of an anabolic hormone in ophthalmology].

Authors:  E de Grosz; C Vereb
Journal:  Arch Ophtalmol Rev Gen Ophtalmol       Date:  1968 Jul-Aug

4.  Study of corneal hydration and corneal uptake of 35S and 45Ca in rats after administration of a single dose of estrogens during the first days of postnatal life.

Authors:  J Obenberger; A Babický; I Ostádalová
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1974

5.  Rabbit testosterone-binding-globulin. II. Effect on androgen metabolism in-vivo.

Authors:  J A Mahoudeau; P Corvol; H Bricaire
Journal:  Endocrinology       Date:  1973-04       Impact factor: 4.736

6.  Corticosterone in the aqueous humour of the rabbit eye.

Authors:  L Stárka; R Hampl; J Obenberger
Journal:  J Steroid Biochem       Date:  1972-01       Impact factor: 4.292

7.  Quantitative determination of endogenous corticosteroids in the rabbit plasma and aqueous humor.

Authors:  J Obenberger; L Stárka; R Hampl
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1971

8.  A further study of a testosterone-binding component of human pregnancy serum.

Authors:  W H Pearlman; I F Fong; J H Tou
Journal:  J Biol Chem       Date:  1969-03-10       Impact factor: 5.157

9.  In vitro estrone-estradiol-17beta interconversion in the cornea, lens, iris and retina of the rabbit eye.

Authors:  L Stárka; J Obenberger
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1975-08-06

10.  Metabolism of 4-14-C-17-beta-3-H-estradiol-17-alpha and 16-14-C-17-alpha-3-H-estradiol-17-beta by the rabbit.

Authors:  K I Williams; D H Henry; D C Collins; D S Layne
Journal:  Endocrinology       Date:  1968-07       Impact factor: 4.736
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  3 in total

1.  Estrogen protects lenses against cataract induced by transforming growth factor-beta (TGFbeta).

Authors:  A M Hales; C G Chamberlain; C R Murphy; J W McAvoy
Journal:  J Exp Med       Date:  1997-01-20       Impact factor: 14.307

2.  Expression of estrogen receptor alpha and 17beta-hydroxysteroid dehydrogenase 4 in the ciliary body.

Authors:  Kaori Kobayashi; Ryo Iwakiri; Hiroshi Kobayashi; Satoshi Okinami
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-11-21       Impact factor: 3.117

3.  Identification of Estrogen Signaling in a Prioritization Study of Intraocular Pressure-Associated Genes.

Authors:  Hannah A Youngblood; Emily Parker; Jingwen Cai; Kristin Perkumas; Hongfang Yu; Jason Sun; Sylvia B Smith; Kathryn E Bollinger; Janey L Wiggs; Louis R Pasquale; Michael A Hauser; W Daniel Stamer; Yutao Liu
Journal:  Int J Mol Sci       Date:  2021-09-24       Impact factor: 6.208
  3 in total

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