Literature DB >> 10846698

[Study of bone mineral density in postmenopausal women with rheumatoid arthritis treated with low dose glucocorticoids].

J M Nolla1, J Fiter, C Gómez Vaquero, L Mateo, J Valverde, D Roig Escofet.   

Abstract

BACKGROUND: To study bone mineral density (BMD) in a group of postmenopausal women with rheumatoid arthritis (RA) treated with low doses of corticosteroids. PATIENTS AND METHODS: One hundred and eleven patients were included. Mean age (SD) was 63.8 (8.8) years, mean duration of postmenopausal period was 16.4 (10.1) years and the mean disease duration was 12.5 (8.2) years.
RESULTS: A significant reduction of lumbar BMD (p < 0.05) and femoral BMD (p < 0.0001) was observed. The prevalence of osteoporosis was of 47%.
CONCLUSIONS: The study supports, in the Spanish population, that postmenopausal women with RA treated with low doses of corticosteroids, have low BMD. We consider that the prevalence of osteoporosis in these patients is high.

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Year:  2000        PMID: 10846698     DOI: 10.1016/s0025-7753(00)71329-7

Source DB:  PubMed          Journal:  Med Clin (Barc)        ISSN: 0025-7753            Impact factor:   1.725


  1 in total

1.  A rational use of glucocorticoids in patients with early arthritis has a minimal impact on bone mass.

Authors:  Monica Ibañez; Ana M Ortiz; Isabel Castrejón; J Alberto García-Vadillo; Inmaculada Carvajal; Santos Castañeda; Isidoro González-Alvaro
Journal:  Arthritis Res Ther       Date:  2010-03-23       Impact factor: 5.156

  1 in total

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