Literature DB >> 10845687

The mechanical properties of compacts of microcrystalline cellulose and silicified microcrystalline cellulose.

S Edge1, D F Steele, A Chen, M J Tobyn, J N Staniforth.   

Abstract

The mechanical properties of compacts of unlubricated microcrystalline cellulose and silicified microcrystalline cellulose were evaluated using the diametric tensile test. The results suggested that, under comparable testing conditions, compacts of silicified microcrystalline cellulose exhibited greater strength than those of microcrystalline cellulose. In addition to enhanced strength, silicified microcrystalline cellulose compacts exhibited greater stiffness and required considerably more energy for tensile failure to occur. Comparison of the data with that obtained for a dry blend of silicon dioxide/microcrystalline cellulose suggested that the functionality benefits of silicification were not due to a simple composite material model.

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Year:  2000        PMID: 10845687     DOI: 10.1016/s0378-5173(00)00343-4

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  3 in total

1.  Surface energy of microcrystalline cellulose determined by capillary intrusion and inverse gas chromatography.

Authors:  D Fraser Steele; R Christian Moreton; John N Staniforth; Paul M Young; Michael J Tobyn; Stephen Edge
Journal:  AAPS J       Date:  2008-10-08       Impact factor: 4.009

2.  Characterization of Mechanical Property Distributions on Tablet Surfaces.

Authors:  Ramon Cabiscol; Jan Henrik Finke; Harald Zetzener; Arno Kwade
Journal:  Pharmaceutics       Date:  2018-10-12       Impact factor: 6.321

Review 3.  Measuring the Mechanical Properties of Plant Cell Walls.

Authors:  Hannes Vogler; Dimitrios Felekis; Bradley J Nelson; Ueli Grossniklaus
Journal:  Plants (Basel)       Date:  2015-03-25
  3 in total

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