R E Thomas1. 1. Memorial University of Newfoundland, St John's. rogert@morgan.ucs.mun.ca
Abstract
OBJECTIVE: To provide evidence-based recommendations for family physicians advising travelers on how to reduce their risk of malaria and dengue fever. QUALITY OF EVIDENCE: A search of MEDLINE from 1990 to November 1998 found 671 articles; randomized controlled trials and systematic reviews were sought. The Cochrane Collaboration was searched for studies relevant to family physicians; meta-analyses of impregnating bed nets with permethrin were found. Health Canada's evidence-based publications were searched; 10 recommendations based on at least one well-conducted randomized trial were found. MAIN MESSAGE: Good evidence-based advice about the efficacy of mefloquine in chloroquine-resistant areas and for pregnant women and children is available, as is advice on the effectiveness of permethrin-impregnated bed nets. CONCLUSIONS: Family physicians can use evidence-based recommendations to advise their patients on how to prevent malaria. The ways in which patients neglect malaria precautions are well-known. For prevention of both malaria and dengue fever, family physicians should counsel their patients to reduce the risk of being bitten by insects.
OBJECTIVE: To provide evidence-based recommendations for family physicians advising travelers on how to reduce their risk of malaria and dengue fever. QUALITY OF EVIDENCE: A search of MEDLINE from 1990 to November 1998 found 671 articles; randomized controlled trials and systematic reviews were sought. The Cochrane Collaboration was searched for studies relevant to family physicians; meta-analyses of impregnating bed nets with permethrin were found. Health Canada's evidence-based publications were searched; 10 recommendations based on at least one well-conducted randomized trial were found. MAIN MESSAGE: Good evidence-based advice about the efficacy of mefloquine in chloroquine-resistant areas and for pregnant women and children is available, as is advice on the effectiveness of permethrin-impregnated bed nets. CONCLUSIONS: Family physicians can use evidence-based recommendations to advise their patients on how to prevent malaria. The ways in which patients neglect malaria precautions are well-known. For prevention of both malaria and dengue fever, family physicians should counsel their patients to reduce the risk of being bitten by insects.
Authors: P Schlagenhauf; H Lobel; R Steffen; R Johnson; K Popp; A Tschopp; R Letz; C Crevoisier Journal: Am J Trop Med Hyg Date: 1997-02 Impact factor: 2.345
Authors: P Schlagenhauf; R Steffen; H Lobel; R Johnson; R Letz; A Tschopp; N Vranjes; Y Bergqvist; O Ericsson; U Hellgren; L Rombo; S Mannino; J Handschin; D Stürchler Journal: Trop Med Int Health Date: 1996-08 Impact factor: 2.622
Authors: M B van Hensbroek; E Onyiorah; S Jaffar; G Schneider; A Palmer; J Frenkel; G Enwere; S Forck; A Nusmeijer; S Bennett; B Greenwood; D Kwiatkowski Journal: N Engl J Med Date: 1996-07-11 Impact factor: 91.245
Authors: R Steffen; E Fuchs; J Schildknecht; U Naef; M Funk; P Schlagenhauf; P Phillips-Howard; C Nevill; D Stürchler Journal: Lancet Date: 1993-05-22 Impact factor: 79.321